A
Arjun B. Prasad
Researcher at National Institutes of Health
Publications - 15
Citations - 2042
Arjun B. Prasad is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Gene nomenclature & Gene. The author has an hindex of 9, co-authored 14 publications receiving 1458 citations. Previous affiliations of Arjun B. Prasad include George Washington University.
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Journal ArticleDOI
Comparative analyses of multi-species sequences from targeted genomic regions
James W. Thomas,James W. Thomas,Jeffrey W. Touchman,Robert W. Blakesley,Gerry Bouffard,Stephen M. Beckstrom-Sternberg,Elliott H. Margulies,Mathieu Blanchette,Adam Siepel,Pamela J. Thomas,Jenny McDowell,Baishali Maskeri,Nancy F. Hansen,M. S. Schwartz,R. J. Weber,W. J. Kent,Donna Karolchik,T. C. Bruen,R. Bevan,David J. Cutler,Scott Schwartz,Laura Elnitski,Jacquelyn R. Idol,Arjun B. Prasad,Shih-Queen Lee-Lin,Valerie Maduro,Tyrone J. Summers,Matthew E. Portnoy,Nicole Dietrich,N. Akhter,K. Ayele,Betty Benjamin,K. Cariaga,Charles P. Brinkley,Shelise Brooks,S. Granite,Xin-Yuan Guan,Jyoti Gupta,P. Haghighi,S. L. Ho,M. C. Huang,Eric Karlins,P. L. Laric,Richelle Legaspi,M. J. Lim,Quino Maduro,Cathy Masiello,Stephen D. Mastrian,J. C. McCloskey,R. Pearson,Sirintorn Stantripop,Emmanuelle Tiongson,J. T. Tran,C. Tsurgeon,Jennifer Vogt,M. A. Walker,Keith Wetherby,L. S. Wiggins,Alice C. Young,L. H. Zhang,Kazutoyo Osoegawa,Baoli Zhu,B. Zhao,C. L. Shu,P. J. De Jong,Charles E. Lawrence,Arian F.A. Smit,Aravinda Chakravarti,David Haussler,Philip Green,Webb Miller,Eric D. Green +71 more
TL;DR: The generation and analysis of over 12 megabases of sequence from 12 species, all derived from the genomic region orthologous to a segment of about 1.8 Mb on human chromosome 7 containing ten genes, show conservation reflecting both functional constraints and the neutral mutational events that shaped this genomic region.
Journal ArticleDOI
Validating the AMRFinder Tool and Resistance Gene Database by Using Antimicrobial Resistance Genotype-Phenotype Correlations in a Collection of Isolates.
Michael Feldgarden,Vyacheslav Brover,Daniel H. Haft,Arjun B. Prasad,Douglas J. Slotta,Igor Tolstoy,Gregory H. Tyson,Shaohua Zhao,Chih-Hao Hsu,Patrick F. McDermott,Daniel A. Tadesse,Cesar A. Morales,Mustafa Simmons,Glenn E. Tillman,Jamie L. Wasilenko,Jason P. Folster,William Klimke +16 more
TL;DR: AMRFinder appears to be a highly accurate AMR gene detection system based on the consistency between predicted AMR genotypes from AMRFinder and resistance phenotypes from the National Antimicrobial Resistance Monitoring System.
Journal ArticleDOI
Confirming the Phylogeny of Mammals by Use of Large Comparative Sequence Data Sets
TL;DR: The results provide support for rooting the placental mammal tree between Atlantogenata and Afrotheria and Boreoeutheria, illustrate the difficulty in resolving some branches even with large amounts of data, and demonstrate the valuable role that very large comparative sequence data sets can play in refining the understanding of the evolutionary relationships of vertebrates.
Journal ArticleDOI
AMRFinderPlus and the Reference Gene Catalog facilitate examination of the genomic links among antimicrobial resistance, stress response, and virulence.
Michael Feldgarden,Vyacheslav Brover,Narjol Gonzalez-Escalona,Jonathan G. Frye,Julie Haendiges,Daniel H. Haft,Maria Hoffmann,James B. Pettengill,Arjun B. Prasad,Glenn E. Tillman,Gregory H. Tyson,William Klimke +11 more
TL;DR: The Reference Gene Catalog (RGC) as discussed by the authors has been extended to include putative acid, biocide, metal, stress resistance genes, in addition to virulence genes and species-specific point mutations.
Journal ArticleDOI
Proposal for assignment of allele numbers for mobile colistin resistance (mcr) genes.
Sally R. Partridge,Vincenzo Di Pilato,Yohei Doi,Michael Feldgarden,Daniel H. Haft,William Klimke,Samir Kumar-Singh,Jian-Hua Liu,Surbhi Malhotra-Kumar,Arjun B. Prasad,Gian Maria Rossolini,Stefan Schwarz,Jianzhong Shen,Timothy R. Walsh,Yang Wang,Basil Britto Xavier +15 more
TL;DR: This work proposes a nomenclature scheme for mcr genes that it hopes will be acceptable to researchers in this area and that will reduce future confusion.