B
Bart N.M. van Berckel
Researcher at VU University Amsterdam
Publications - 336
Citations - 12883
Bart N.M. van Berckel is an academic researcher from VU University Amsterdam. The author has contributed to research in topics: Dementia & Medicine. The author has an hindex of 57, co-authored 282 publications receiving 10176 citations. Previous affiliations of Bart N.M. van Berckel include VU University Medical Center & Utrecht University.
Papers
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Journal ArticleDOI
Microglia activation in recent-onset schizophrenia: a quantitative (R)-[11C]PK11195 positron emission tomography study
Bart N.M. van Berckel,Matthijs G. Bossong,Ronald Boellaard,Reina W. Kloet,Alie Schuitemaker,E. Caspers,Gert Luurtsema,Albert D. Windhorst,Wiepke Cahn,Adriaan A. Lammertsma,René S. Kahn +10 more
TL;DR: Activated microglia are present in schizophrenia patients within the first 5 years of disease onset, which suggests that, in this period, neuronal injury is present and that neuronal damage may be involved in the loss of gray matter associated with this disease.
Journal ArticleDOI
Prevalence of amyloid PET positivity in dementia syndromes: a meta-analysis.
Rik Ossenkoppele,Willemijn J. Jansen,Gil D. Rabinovici,Dirk L. Knol,Wiesje M. van der Flier,Bart N.M. van Berckel,Philip Scheltens,Pieter Jelle Visser,Sander C.J. Verfaillie,Marissa D. Zwan,Sofie Adriaanse,Adriaan A. Lammertsma,Frederik Barkhof,William J. Jagust,Bruce L. Miller,Howard J. Rosen,Susan M. Landau,Victor L. Villemagne,Christopher C. Rowe,Dong Y. Lee,Duk L. Na,Sang W. Seo,Marie Sarazin,Catherine M. Roe,Osama Sabri,Henryk Barthel,Norman Koglin,John R. Hodges,Cristian E. Leyton,Rik Vandenberghe,Koen Van Laere,Alexander Drzezga,Stefan Förster,Timo Grimmer,Pascual Sánchez-Juan,José M. Carril,Vincent Mok,Vincent Camus,William E. Klunk,Ann D. Cohen,Philipp T. Meyer,Sabine Hellwig,Andrew B. Newberg,Kristian Steen Frederiksen,Adam S. Fleisher,Mark A. Mintun,David A. Wolk,Agneta Nordberg,Juha O. Rinne,Gaël Chételat,Alberto Lleó,Rafael Blesa,Juan Fortea,Karine Madsen,Karen M. Rodrigue,David J. Brooks +55 more
TL;DR: Findings indicate the potential clinical utility of amyloid imaging for differential diagnosis in early-onset dementia and to support the clinical diagnosis of participants with AD dementia and noncarrier APOE ε4 status.
Journal ArticleDOI
The behavioural/dysexecutive variant of Alzheimer's disease: clinical, neuroimaging and pathological features.
Rik Ossenkoppele,Yolande A.L. Pijnenburg,David C. Perry,Brendan I. Cohn-Sheehy,Nienke M.E. Scheltens,Jacob W. Vogel,Joel H. Kramer,Annelies E. van der Vlies,Renaud La Joie,Howard J. Rosen,Wiesje M. van der Flier,Lea T. Grinberg,Annemieke J.M. Rozemuller,Eric J. Huang,Bart N.M. van Berckel,Bruce L. Miller,Frederik Barkhof,William J. Jagust,Philip Scheltens,William W. Seeley,Gil D. Rabinovici,Gil D. Rabinovici +21 more
TL;DR: Behavioural Alzheimer's disease presentations are characterized by a milder and more restricted behavioural profile than in behavioural variant frontotemporal dementia, co-occurrence of memory dysfunction and high APOE ε4 prevalence.
Journal ArticleDOI
Delta 9-tetrahydrocannabinol induces dopamine release in the human striatum.
Matthijs G. Bossong,Bart N.M. van Berckel,Bart N.M. van Berckel,Ronald Boellaard,Lineke Zuurman,Robert C. Schuit,Albert D. Windhorst,Joop M. A. van Gerven,Nick F. Ramsey,Adriaan A. Lammertsma,René S. Kahn +10 more
TL;DR: It is shown that Δ9-tetrahydrocannabinol (THC), the main psychoactive component in cannabis, induces dopamine release in the human striatum, implying that the endogenous cannabinoid system is involved in regulating striatal dopamine release.
Journal ArticleDOI
Resting-state fMRI changes in Alzheimer's disease and mild cognitive impairment.
Maja Binnewijzend,Menno M. Schoonheim,Ernesto J. Sanz-Arigita,Alle Meije Wink,Wiesje M. van der Flier,Nelleke Tolboom,Sofie Adriaanse,Jessica S. Damoiseaux,Philip Scheltens,Bart N.M. van Berckel,Frederik Barkhof +10 more
TL;DR: Clinical relevant decreased FC within the default-mode network (DMN) in the precuneus and posterior cingulate cortex compared with controls was observed in Alzheimer's disease.