다중혈관 관상동맥 환자에서 y-문합을 이용하여 양쪽 내흉동맥만을 사용한 우회술의 조기 성적

Authors/Task Force Members: John J.V. McMurray (Chairperson) (UK)*, Stamatis Adamopoulos (Greece), Stefan D. Anker (Germany), Angelo Auricchio (Switzerland), Michael Böhm (Germany), Kenneth Dickstein (Norway), Volkmar Falk (Switzerland), Gerasimos Filippatos (Greece), Cândida Fonseca (Portugal), Miguel Angel Gomez-Sanchez (Spain), Tiny Jaarsma (Sweden), Lars Køber (Denmark), Gregory Y.H. Lip (UK), Aldo Pietro Maggioni (Italy), Alexander Parkhomenko (Ukraine), Burkert M. Pieske (Austria), Bogdan A. Popescu (Romania), Per K. Rønnevik (Norway), Frans H. Rutten (The Netherlands), Juerg Schwitter (Switzerland), Petar Seferovic (Serbia), Janina Stepinska (Poland), Pedro T. Trindade (Switzerland), Adriaan A. Voors (The Netherlands), Faiez Zannad (France), Andreas Zeiher (Germany).

ESC Guidelines for the Diagnosis And Treatment of Acute And Chronic Heart Failure 2008

ESC guidelines for the diagnosis and treatment of acute and chronic heart failure 2012 : The Task Force for the Diagnosis and Treatment of Acute and Chronic Heart Failure 2012 of the European Society of Cardiology. Developed in collaboration with the Heart Failure Association (HFA) of the ESC

https://anmco.it/uploads/u_cms/media/2014/12/798e9298d77b7b8c9aa0514e43fe95a2.pdf

ESC guidelines for the diagnosis and treatment of acute and chronic heart failure 2012: The Task Force for the Diagnosis and Treatment of Acute and Chronic Heart Failure 2012 of the European Society of Cardiology. Developed in collaboration with the Heart Failure Association (HFA) of the ESC.

March 5, 2019 e1 WRITING GROUP MEMBERS Emelia J. Benjamin, MD, ScM, FAHA, Chair Paul Muntner, PhD, MHS, FAHA, Vice Chair Alvaro Alonso, MD, PhD, FAHA Marcio S. Bittencourt, MD, PhD, MPH Clifton W. Callaway, MD, FAHA April P. Carson, PhD, MSPH, FAHA Alanna M. Chamberlain, PhD Alexander R. Chang, MD, MS Susan Cheng, MD, MMSc, MPH, FAHA Sandeep R. Das, MD, MPH, MBA, FAHA Francesca N. Delling, MD, MPH Luc Djousse, MD, ScD, MPH Mitchell S.V. Elkind, MD, MS, FAHA Jane F. Ferguson, PhD, FAHA Myriam Fornage, PhD, FAHA Lori Chaffin Jordan, MD, PhD, FAHA Sadiya S. Khan, MD, MSc Brett M. Kissela, MD, MS Kristen L. Knutson, PhD Tak W. Kwan, MD, FAHA Daniel T. Lackland, DrPH, FAHA Tené T. Lewis, PhD Judith H. Lichtman, PhD, MPH, FAHA Chris T. Longenecker, MD Matthew Shane Loop, PhD Pamela L. Lutsey, PhD, MPH, FAHA Seth S. Martin, MD, MHS, FAHA Kunihiro Matsushita, MD, PhD, FAHA Andrew E. Moran, MD, MPH, FAHA Michael E. Mussolino, PhD, FAHA Martin O’Flaherty, MD, MSc, PhD Ambarish Pandey, MD, MSCS Amanda M. Perak, MD, MS Wayne D. Rosamond, PhD, MS, FAHA Gregory A. Roth, MD, MPH, FAHA Uchechukwu K.A. Sampson, MD, MBA, MPH, FAHA Gary M. Satou, MD, FAHA Emily B. Schroeder, MD, PhD, FAHA Svati H. Shah, MD, MHS, FAHA Nicole L. Spartano, PhD Andrew Stokes, PhD David L. Tirschwell, MD, MS, MSc, FAHA Connie W. Tsao, MD, MPH, Vice Chair Elect Mintu P. Turakhia, MD, MAS, FAHA Lisa B. VanWagner, MD, MSc, FAST John T. Wilkins, MD, MS, FAHA Sally S. Wong, PhD, RD, CDN, FAHA Salim S. Virani, MD, PhD, FAHA, Chair Elect On behalf of the American Heart Association Council on Epidemiology and Prevention Statistics Committee and Stroke Statistics Subcommittee

Heart Disease and Stroke Statistics—2019 Update: A Report From the American Heart Association

ALAT
: alanine aminotransferase
ASAT
: aspartate aminotransferase
APAH
: associated pulmonary arterial hypertension
BAS
: balloon atrial septostomy
BMPR2
: bone morphogenetic protein receptor 2
BNP
: brain natriuretic peptide
BPA
: balloon pulmonary angioplasty
BREATHE
: Bosentan

/pdf/2015-esc-ers-guidelines-for-the-diagnosis-and-treatment-of-y26yabnnom.pdf

2015 ESC/ERS Guidelines for the diagnosis and treatment of pulmonary hypertension: The Joint Task Force for the Diagnosis and Treatment of Pulmonary Hypertension of the European Society of Cardiology (ESC) and the European Respiratory Society (ERS): Endorsed by: Association for European Paediatric and Congenital Cardiology (AEPC), International Society for Heart and Lung Transplantation (ISHLT).

In order to separate the HC-emissions from two-stroke engines into short-circuit losses and emissions due to incomplete combustion, Laser Induced Fluorescence (LIF) measurements were performed on the exhaust gases just outside the exhaust ports of two engines of different designs. The difference between the two engines was the design of the transfer channels. One engine had "finger" transfer channels and one had "cup handle" transfer channels. Apart from that they were similar. The engine with "finger" transfer channels was earlier known to give more short-circuiting losses than the other engine, and that behavior was confirmed by these measurements. Generally, the results show that the emission of hydrocarbons has two peaks, one just after exhaust port opening and one late in the scavenging phase. The spectral information shows differences between the two peaks and it can be concluded that the latter peak is due to short-circuiting and the earlier due to incomplete combustion. The flow outside the exhaust port was measured with Laser Doppler Velocimetry (LDV). These measurements confirm the occurrence of two emission peaks. (Less)

/pdf/crank-angle-resolved-hc-detection-using-lif-in-the-exhausts-qgjawuuooh.pdf

Crank Angle Resolved HC Detection Using LIF in the Exhausts of Small Two-Stroke Engines Running at High Engine Speed

Progressive conduction disease late after adriamycin treatment of lymphoma, despite normalised ejection fraction

An experimental study was carried out to investigate the combustion process and particulate matter (PM) emission characteristics in a spray guided direct injection spark ignition (DISI) engine under lean-stratified operation. In-cylinder pressure analysis, PM emission measurement, and visualization of the in-cylinder combustion were applied. Heat release rate during stratified combustion showed 2-staged combustion characteristics. The main combustion was preceded with fast combustion speed and high peak of heat release rate. Combustion process after the main combustion showed longer combustion duration and relatively lower intensity of heat release rate. Propagation of non-luminous blue flame was observed during the early stage of the main combustion process. Mixing controlled combustion with luminous sooting flame development was observed during the late stage of the main combustion. Lastly, non-luminous blue flame was dominant during the secondary combustion process, which was interpreted as the combustion of the unburned lean-homogeneous mixture. PM emission characteristics were investigated under various injection timing conditions. The number and total weight of PM emission were increased as the injection timing was retarded. These trends were coincident with the trend of sooting flame luminosity during the combustion process with variation of injection timing. PM emission and mixing controlled combustion were found to have mainly originated from the inhomogeneous gas phase distribution of the stratified mixture.

Combustion process and PM emission characteristics in a stratified DISI engine under low load condition

Cardiovascular magnetic resonance (CMR) is an increasingly used imaging tool in cardiology. Initially, technical resources and access to trained staff were limited to a few centers. As scanners become more available and thanks to widespread training of cardiologists and technicians, CMR can now be performed in most cardiology centers. Without exposing the patient to ionizing radiation, a comprehensive cardiac study can be performed in 30–45 min, depending on clinical problem and scanner capabilities. A typical cardiac exam consists of anatomical images for gross anatomy and cine images for the evaluation of ventricular function. Depending on the clinical problem, a number of additional techniques can be added. Using chelated gadolinium contrast agents, first pass myocardial perfusion can be analyzed during pharmacological stress for the diagnosis of coronary artery disease. After injection of contrast in a peripheral vein, high resolution angiography can be performed. Phase contrast velocity maps (which despite the terminology it does not include contrast agents) can also be used to analyze intrathoracic vascular blood flow and flow velocity.

Cardiovascular Magnetic Resonance in Heart Failure

Purpose Treating localized prostate cancer (PC) with combination radiotherapy consisting of external beam radiotherapy (EBRT) and high-dose-rate brachytherapy (HDR-BT) has been proven to result in better disease outcome than EBRT only. We aimed to evaluate the incidence of toxicities due to combination therapy and identify parameters correlated to acute or late urinary, rectal, and erectile toxicities. Material and methods Data on symptoms and tumor/treatment parameters were collected from 359 patients treated between 2008 and 2018 with EBRT (42 Gy in 14 fractions) and HDR-BT (14.5 Gy in one fraction) for localized PC, at the Örebro University Hospital. Urinary, rectal, and erectile symptoms were presented descriptively, and bivariate analyses for correlation between grade ≥ 2 toxicity and potential predictors were performed. To evaluate prognostic models, multivariable analyses were applied. Results Urinary toxicity grade ≥ 2 was observed in 154 patients (47% of patients without pre-existing symptoms grade ≥ 2), of which 15 were grade 3. Rectal toxicity grade 2 was observed in 22 (6%) patients. Any grade erectile dysfunction was evident in all patients without pre-existing dysfunction (n = 103), whereas only 7 recovered completely. In bivariate analyses age was correlated with higher risk of acute urinary toxicity, and irradiated volume was associated with both urinary and rectal toxicities. However, we found no multivariable model of clinical and statistical significance to predict the risk of urinary or rectal toxicities. Conclusions In our study cohort, the severity of toxicities was in general mild or moderate and temporary, whereas the incidence of severe toxicity was considerably low. Although we found no predictive models for toxicities, our findings are reassuring that this treatment approach as curative therapy for localized PC is well-tolerated.

/pdf/predicting-toxicity-caused-by-high-dose-rate-brachytherapy-6z3osno1.pdf

Bengt Johansson

Papers

Crank Angle Resolved HC Detection Using LIF in the Exhausts of Small Two-Stroke Engines Running at High Engine Speed

Progressive conduction disease late after adriamycin treatment of lymphoma, despite normalised ejection fraction

Combustion process and PM emission characteristics in a stratified DISI engine under low load condition

Cardiovascular Magnetic Resonance in Heart Failure

Predicting toxicity caused by high-dose-rate brachytherapy single boost for prostate cancer