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Benjamin Meder
Researcher at Heidelberg University
Publications - 226
Citations - 9623
Benjamin Meder is an academic researcher from Heidelberg University. The author has contributed to research in topics: Dilated cardiomyopathy & Medicine. The author has an hindex of 49, co-authored 198 publications receiving 7530 citations. Previous affiliations of Benjamin Meder include University Hospital Heidelberg & Stanford University.
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Journal ArticleDOI
Divergent effects of GM-CSF and TGFβ1 on bone marrow-derived macrophage arginase-1 activity, MCP-1 expression, and matrix metalloproteinase-12: a potential role during arteriogenesis
Marco Jost,Elena Ninci,Benjamin Meder,Caroline Kempf,Niels van Royen,Jing Hua,Bernhard J. Berger,Imo E. Hoefer,Manuel Modolell,Ivo Buschmann +9 more
TL;DR: The hypothesis that arteriogenesis is a multistage mechanism, including monocyte/macrophage adhesion and transmigration, pro‐arteriogenic cytokine expression, degradation of connective tissue, and collagen synthesis regulation, is supported.
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Refining Diagnostic MicroRNA Signatures by Whole-miRNome Kinetic Analysis in Acute Myocardial Infarction
Britta Vogel,Andreas Keller,Andreas Keller,Karen S. Frese,Wanda Kloos,Elham Kayvanpour,Farbod Sedaghat-Hamedani,Sarah Hassel,Sabine Marquart,Markus Beier,Evangelos Giannitsis,Stefan E. Hardt,Hugo A. Katus,Benjamin Meder +13 more
TL;DR: The present proof-of-concept study provides novel insights into the dynamic changes of the human miRNome during AMI, finding a subset of miRNAs to be significantly dysregulated both at initial presentation and during the course of AMI.
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In-vivo characterization of human dilated cardiomyopathy genes in zebrafish.
Britta Vogel,Benjamin Meder,Steffen Just,Christina Laufer,Ina M. Berger,Sabrina Weber,Hugo A. Katus,Wolfgang Rottbauer +7 more
TL;DR: The results indicate that the zebrafish is a suitable model organism to rapidly evaluate novel DCM disease genes in-vivo and gene-specific differences which are also seen in human DCM can be reliably reproduced in theZebrafish model.
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Identification and Functional Characterization of Hypoxia-Induced Endoplasmic Reticulum Stress Regulating lncRNA (HypERlnc) in Pericytes.
Florian Bischoff,Astrid Werner,David John,Jes-Niels Boeckel,Maria-Theodora Melissari,Phillip Grote,Simone F. Glaser,Shemsi Demolli,Shizuka Uchida,Katharina M. Michalik,Benjamin Meder,Hugo A. Katus,Jan Haas,Wei Chen,Soni Savai Pullamsetti,Werner Seeger,Andreas M. Zeiher,Stefanie Dimmeler,Christoph M. Zehendner +18 more
TL;DR: It is shown that HypERlnc regulates human pericyte function and the endoplasmic reticulum stress response, and its role in human cardiopulmonary disease states is indicated.
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Validating Alzheimer's disease micro RNAs using next-generation sequencing.
Andreas Keller,Christina Backes,Jan Haas,Petra Leidinger,Walter Maetzler,Christian Deuschle,Daniela Berg,Christoph Ruschil,Valentina Galata,Klemens Ruprecht,Cord F. Stähler,Maximilian L. Würstle,Daniel Sickert,Manfred Gogol,Benjamin Meder,Eckart Meese +15 more
TL;DR: A 12‐micro RNA (miRNA) blood‐based signature is reported using next‐generation sequencing (NGS) of 54 AD cases and 22 controls to support detection and improved care for patients.