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Benjamin Meder
Researcher at Heidelberg University
Publications - 226
Citations - 9623
Benjamin Meder is an academic researcher from Heidelberg University. The author has contributed to research in topics: Dilated cardiomyopathy & Medicine. The author has an hindex of 49, co-authored 198 publications receiving 7530 citations. Previous affiliations of Benjamin Meder include University Hospital Heidelberg & Stanford University.
Papers
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Doxorubicin induces cardiotoxicity in a pluripotent stem cell model of aggressive B cell lymphoma cancer patients
Luis Haupt,Andreas Maus,Malte Tiburcy,Steffen Koehne,Wiebke Maurer,Rewati Tappu,Jan Haas,Yun Li,André Sasse,Celio X.C. Santos,Ralf Dressel,Leszek Wojnowski,Gertrude Bunt,Ajay M. Shah,Benjamin Meder,Samuel Sossalla,Bernd Wollnik,Gerd Hasenfuss,Katrin Streckfuß-Bömeke +18 more
TL;DR: The results suggest thatDOX-related stress resulted in decreased contractile activity and finally in heart failure in ACT patients, and the first human iPSC-CM and EHM model of DOX-induced cardiac dysfunction in patients with B-cell lymphoma is developed.
Journal ArticleDOI
RBM20-Related Cardiomyopathy: Current Understanding and Future Options
Jan Koelemen,Michael Gotthardt,Michael Gotthardt,Lars M. Steinmetz,Lars M. Steinmetz,Benjamin Meder,Benjamin Meder +6 more
TL;DR: In this article, a review article highlights some of the recent advances in the field, ranging from aspects of granule formation to 3D genome architectures underlying RBM20-related cardiomyopathy.
Journal ArticleDOI
Prevalence and clinical outcomes of dystrophin-associated dilated cardiomyopathy without severe skeletal myopathy
María Alejandra Restrepo-Córdoba,Karim Wahbi,Anca Florian,Juan Jiménez-Jáimez,Luisa Politano,Michael Arad,Vicente Climent-Payá,Ana García-Álvarez,Rasmus B Hansen,José M. Larrañaga-Moreira,Miloš Kubánek,Luis R. Lopes,Luis R. Lopes,Andrea Ros,Ruxandra Jurcut,Torsten Bloch Rasmussen,Luis Ruiz-Guerrero,Regina Pribe-Wolferts,Julián Palomino-Doza,Zofia T. Bilińska,José Rodríguez-Palomares,Rosa L. E. van Loon,Maria Teresa Basurte Elorz,Giovanni Quarta,Maria Robledo Iñarritu,Job A J Verdonschot,Tanya Stojkovic,Zornitsa Shomanova,Francisco Bermúdez-Jiménez,Alberto Palladino,Dov Freimark,María I. García-Álvarez,Paloma Jordà,Fernando Domínguez,Juan Pablo Ochoa,Francesca Girolami,Ramon Brugada,Benjamin Meder,Benjamin Meder,Roberto Barriales-Villa,Jens Mogensen,Pascal Laforêt,Ali Yilmaz,Perry M. Elliott,Perry M. Elliott,Pablo García-Pavía +45 more
TL;DR: In this article, the authors describe the phenotype and prognosis of dystrophin gene associated dilated cardiomyopathy in DMD mutation carriers without severe skeletal myopathy and conclude that the onset of DCM onset is the major determinant of prognosis with similar survival regardless of the presence of skeletalmyopathy.
Journal ArticleDOI
Epigenetic Regulation of Alternative mRNA Splicing in Dilated Cardiomyopathy.
Weng-Tein Gi,Jan Haas,Farbod Sedaghat-Hamedani,Elham Kayvanpour,Rewati Tappu,David H. Lehmann,Omid Shirvani Samani,Michael Wisdom,Andreas Keller,Hugo A. Katus,Benjamin Meder +10 more
TL;DR: This study highlights for the first time the close interrelationship between genetic imprinting by DNA methylation and the transport of this epigenetic information towards the dynamic mRNA splicing landscape.
Patent
Complex sets of mirnas as non-invasive biomarkers for early diagnosis of acute myocardial infarction
TL;DR: In this paper, the authors proposed non-invasive methods for early diagnosis and/or differential diagnosis of acute myocardial infarction in a blood sample of a subject by determining the level of at least one miRNA selected from hsa-miR-7-1*, hsaR-566, hsa R-455-3p, Hsa R R-1254, HSA R R 1254, hs R R R 636, Hs R 2, hsa r R 1915.