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Bernard E. Ebruke
Researcher at Medical Research Council
Publications - 42
Citations - 3290
Bernard E. Ebruke is an academic researcher from Medical Research Council. The author has contributed to research in topics: Pneumonia & Medicine. The author has an hindex of 20, co-authored 37 publications receiving 2207 citations. Previous affiliations of Bernard E. Ebruke include University of London.
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Journal ArticleDOI
Chest Radiograph Findings in Childhood Pneumonia Cases From the Multisite PERCH Study
Nicholas Fancourt,Nicholas Fancourt,Maria Deloria Knoll,Henry C. Baggett,W. Abdullah Brooks,W. Abdullah Brooks,Daniel R. Feikin,Daniel R. Feikin,Laura L. Hammitt,Laura L. Hammitt,Stephen R. C. Howie,Stephen R. C. Howie,Stephen R. C. Howie,Karen L. Kotloff,Orin S. Levine,Orin S. Levine,Shabir A. Madhi,Shabir A. Madhi,David R. Murdoch,David R. Murdoch,J. Anthony G. Scott,J. Anthony G. Scott,Donald M. Thea,Juliet O. Awori,Breanna Barger-Kamate,James Chipeta,Andrea DeLuca,Mahamadou Diallo,Amanda J. Driscoll,Bernard E. Ebruke,Melissa M. Higdon,Yasmin Jahan,Ruth A. Karron,Nasreen Mahomed,David P. Moore,David P. Moore,Kamrun Nahar,Sathapana Naorat,Micah Silaba Ominde,Daniel E. Park,Daniel E. Park,Christine Prosperi,Somwe Wa Somwe,Somsak Thamthitiwat,Syed M. A. Zaman,Syed M. A. Zaman,Scott L. Zeger,Katherine L. O'Brien +47 more
TL;DR: In the Pneumonia Etiology Research for Child Health study, abnormal chest radiographs in cases were associated with hypoxemia, crackles, tachypnea, and fever and Consolidation on CXR was associated with an increased risk of mortality.
Journal ArticleDOI
Etiology of Severe Childhood Pneumonia in The Gambia, West Africa, Determined by Conventional and Molecular Microbiological Analyses of Lung and Pleural Aspirate Samples
Stephen R. C. Howie,Gerard A. J. Morris,Rafal Tokarz,Bernard E. Ebruke,Eunice M. Machuka,Readon C. Ideh,Osaretin Chimah,Ousman Secka,John Townend,Michel M. Dione,Claire Oluwalana,Malick Njie,Mariatou Jallow,Philip C. Hill,Martin Antonio,Brian Greenwood,Thomas Briese,Kim Mulholland,Tumani Corrah,W. Ian Lipkin,Richard A. Adegbola,Richard A. Adegbola +21 more
TL;DR: In this article, molecular analyses of lung aspirates from Gambian children with severe pneumonia detected pathogens more frequently than did culture and showed a predominance of bacteria, principally Streptococcus pneumoniae, >75% being of serotypes covered by current pneumococcal conjugate vaccines.
Journal ArticleDOI
Discovery and Validation of Biomarkers to Guide Clinical Management of Pneumonia in African Children
Honglei Huang,Readon C. Ideh,Evelyn Gitau,Marie L. Thézénas,Muminatou Jallow,Bernard E. Ebruke,Osaretin Chimah,Claire Oluwalana,Henri Karanja,Grant A. Mackenzie,Richard A. Adegbola,Dominic P. Kwiatkowski,Benedikt M. Kessler,James A. Berkley,Stephen R. C. Howie,Climent Casals-Pascual +15 more
TL;DR: Lipocalin 2 distinguishes severe and bacterial pneumonia from nonsevere and nonbacterial pneumonia with a high level of precision and requires large-scale clinical evaluation.
Journal ArticleDOI
Global burden of acute lower respiratory infection associated with human metapneumovirus in children under 5 years in 2018: a systematic review and modelling study.
Xin Wang,You Li,Maria Deloria-Knoll,Shabir A. Madhi,Cheryl Cohen,Asad Ali,Sudha Basnet,Sudha Basnet,Quique Bassat,W. Abdullah Brooks,Malinee Chittaganpitch,Marcela Echavarria,Rodrigo Fasce,Doli Goswami,Siddhivinayak Hirve,Nusrat Homaira,Nusrat Homaira,Stephen R. C. Howie,Stephen R. C. Howie,Karen L. Kotloff,Najwa Khuri-Bulos,Anand Krishnan,Marilla G. Lucero,Socorro Lupisan,Ainara Mira-Iglesias,David P. Moore,Cinta Moraleda,Cinta Moraleda,Marta C. Nunes,Histoshi Oshitani,Betty E Owor,Fernando P. Polack,Katherine L. O'Brien,Zeba A Rasmussen,Barbara Rath,Vahid Salimi,J. Anthony G. Scott,J. Anthony G. Scott,J. Anthony G. Scott,Eric A. F. Simões,Tor A. Strand,Donald M. Thea,Florette K. Treurnicht,Linda Cheyenne Vaccari,Lay-Myint Yoshida,Heather J. Zar,Harry Campbell,Harish Nair,Romina Libster,Grieven P. Otieno,Imane Joundi,Shobha Broor,Mark P. Nicol,Ritvik Amarchand,Ting Shi,F. Xavier López-Labrador,Julia M Baker,Alexandra Jamison,Avinash Choudekar,Sanjay Juvekar,Patrick Obermeier,Brunhilde Schweiger,Lola Madrid,Elizabeth D. Thomas,Miguel A. Lanaspa,Hanna Nohynek,James Nokes,Marta Werner,Anh Danhg,Mandeep S. Chadha,Joan Puig-Barberà,Mauricio T. Caballero,Maria Mathisen,Sibongile Walaza,Orienka Hellferscee,Matt Laubscher,Melissa M. Higdon,Meredith Haddix,Pongpun Sawatwong,Henry C. Baggett,Phil Seidenberg,Lawrence Mwanayanda,Martin Antonio,Bernard E. Ebruke,Tanja Adams,Mustafizur Rahman,Mohammed Ziaur Rahman,Samboa O. Sow,Vicky L. Baillie,Lesley Workman,Michiko Toizumi,Milagritos D. Tapia,Thi hien anh Nguyen,Susan C. Morpeth +93 more
TL;DR: The authors in this article estimated the global burden of human metapneumovirus-associated ALRIs in children younger than 5 years from a systematic review of 119 studies published between Jan 1, 2001, and Dec 31, 2019, and 40 high quality unpublished studies.
Etiology of Severe Childhood Pneumonia in The Gambia, West Africa, Determined by Conventional
Stephen R. C. Howie,Gerard A. J. Morris,Rafal Tokarz,Bernard E. Ebruke,Eunice M. Machuka,Readon C. Ideh,Osaretin Chimah,Ousman Secka,John Townend,Michel M. Dione,Claire Oluwalana,Malick Njie,Mariatou Jallow,Philip C. Hill,Martin Antonio,Brian Greenwood,Thomas Briese,Kim Mulholland,Tumani Corrah,W. Ian Lipkin,Richard A. Adegbola,New Zealand +21 more
TL;DR: Molecular analyses of lung aspirates from Gambian children with severe pneumonia detected pathogens more frequently than did culture and showed a predominance of bacteria, principally Streptococcuspneumoniae, >75% being of serotypes covered by current pneumococcal conjugate vaccines.