B
Bernd Timmermann
Researcher at Max Planck Society
Publications - 161
Citations - 27435
Bernd Timmermann is an academic researcher from Max Planck Society. The author has contributed to research in topics: Gene & Genome. The author has an hindex of 45, co-authored 146 publications receiving 19299 citations. Previous affiliations of Bernd Timmermann include Max Delbrück Center for Molecular Medicine & University of Bergen.
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Journal ArticleDOI
The bromodomain protein BRD4 regulates the KEAP1/NRF2-dependent oxidative stress response.
Michelle Hussong,Stefan T. Börno,Martin Kerick,Andrea Wunderlich,A Franz,Holger Sültmann,Bernd Timmermann,Hans Lehrach,M Hirsch-Kauffmann,Michal R. Schweiger +9 more
TL;DR: This work generated an expression signature of BRD4 knockdown cells and found oxidative stress response genes significantly enriched and highlighted BRD 4 as signal transducer of the cellular response to oxidative stress.
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The Saccharomyces cerevisiae W303-K6001 cross-platform genome sequence: insights into ancestry and physiology of a laboratory mutt
Markus Ralser,Markus Ralser,Heiner Kuhl,Meryem Ralser,Martin Werber,Hans Lehrach,Michael Breitenbach,Bernd Timmermann +7 more
TL;DR: The W303-K6001 genome pictures details of complex genetic relationships between the model strains that date back to the early days of experimental yeast genetics, underlines the necessity of combining multiple NGS and genome-assembling techniques for achieving accurate variant calling in genomic studies.
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The CatSper channel controls chemosensation in sea urchin sperm
Reinhard Seifert,Reinhard Seifert,Melanie Flick,Wolfgang Bönigk,Luis Alvarez,Christian Trötschel,Ansgar Poetsch,Astrid Müller,Normann Goodwin,Normann Goodwin,Patric Pelzer,Patric Pelzer,Nachiket D. Kashikar,Nachiket D. Kashikar,Elisabeth Kremmer,Jan F. Jikeli,Bernd Timmermann,Heiner Kuhl,Dmitry Fridman,Dmitry Fridman,Florian Windler,Florian Windler,U. Benjamin Kaupp,U. Benjamin Kaupp,Timo Strünker,Timo Strünker +25 more
TL;DR: CatSper mediates the chemoattractant‐evoked Ca2+ influx and controls chemotactic steering and a concomitant alkalization serves as a highly cooperative mechanism that enables CatSper to transduce periodic voltage changes into Ca2- bursts.
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Odd skipped-related 1 identifies a population of embryonic fibro-adipogenic progenitors regulating myogenesis during limb development
Pedro Vallecillo-García,Pedro Vallecillo-García,Mickael Orgeur,Sophie vom Hofe-Schneider,Jürgen Stumm,Jürgen Stumm,Verena Kappert,Verena Kappert,Daniel M. Ibrahim,Stefan T. Börno,Shinichiro Hayashi,Shinichiro Hayashi,Frédéric Relaix,Frédéric Relaix,Katrin Hildebrandt,Gerhard Sengle,Manuel Koch,Bernd Timmermann,Giovanna Marazzi,Giovanna Marazzi,David Sassoon,David Sassoon,Delphine Duprez,Delphine Duprez,Sigmar Stricker,Sigmar Stricker +25 more
TL;DR: It is shown here that mouse embryonic limb MCT cells expressing the transcription factor Osr1, differentiate into fibrogenic and adipogenic cells in vivo and in vitro defining an embryonic FAP-like population, and genetic lineage tracing shows that developmental OsR1+ cells give rise to a subset of adult FAPs.
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An Unbiased Molecular Approach Using 3'-UTRs Resolves the Avian Family-Level Tree of Life.
Heiner Kuhl,Heiner Kuhl,Carolina Frankl-Vilches,Antje Bakker,Gerald Mayr,Gerhard Nikolaus,Stefan Boerno,Sven Klages,Bernd Timmermann,Manfred Gahr +9 more
TL;DR: As 3′-UTR-based phylotranscriptomics resolved the avian family-level tree of life, it is suggested that this procedure will also resolve the all-species avian tree oflife.