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Bruce Hoff
Researcher at Sage Bionetworks
Publications - 13
Citations - 713
Bruce Hoff is an academic researcher from Sage Bionetworks. The author has contributed to research in topics: Breast cancer & Markov chain Monte Carlo. The author has an hindex of 11, co-authored 13 publications receiving 531 citations.
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Journal ArticleDOI
Evaluation of Combined Artificial Intelligence and Radiologist Assessment to Interpret Screening Mammograms
Thomas Schaffter,Diana S. M. Buist,Christoph I. Lee,Yaroslav Nikulin,Dezső Ribli,Yuanfang Guan,William Lotter,Zequn Jie,Hao Du,Sijia Wang,Jiashi Feng,Mengling Feng,Hyo-Eun Kim,F. Albiol,Alberto Albiol,Stephen Morrell,Zbigniew Wojna,Mehmet Eren Ahsen,Umar Asif,Antonio Jimeno Yepes,Shivanthan A.C. Yohanandan,Simona Rabinovici-Cohen,Darvin Yi,Bruce Hoff,Thomas Yu,Elias Chaibub Neto,Daniel L. Rubin,Peter Lindholm,Laurie R. Margolies,Russell B. McBride,Joseph H. Rothstein,Weiva Sieh,Rami Ben-Ari,Stefan Harrer,Andrew D. Trister,Stephen H. Friend,Thea Norman,Berkman Sahiner,Fredrik Strand,Fredrik Strand,Justin Guinney,Gustavo Stolovitzky,Lester Mackey,Joyce Cahoon,Li Shen,Jae Ho Sohn,Hari Trivedi,Yiqiu Shen,Ljubomir Buturovic,Jose Costa Pereira,Jaime S. Cardoso,Eduardo Castro,Karl Trygve Kalleberg,Obioma Pelka,Imane Nedjar,Krzysztof J. Geras,Felix Nensa,Ethan Goan,Sven Koitka,Sven Koitka,Luis Caballero,David D. Cox,Pavitra Krishnaswamy,Gaurav Pandey,Christoph M. Friedrich,Dimitri Perrin,Clinton Fookes,Bibo Shi,Gerard Cardoso Negrie,Michael Kawczynski,Kyunghyun Cho,Can Son Khoo,Joseph Y. Lo,A. Gregory Sorensen,Hwejin Jung +74 more
TL;DR: This diagnostic accuracy study evaluates whether artificial intelligence can overcome human mammography interpretation limits with a rigorous, unbiased evaluation of machine learning algorithms.
Journal ArticleDOI
Systematic Analysis of Challenge-Driven Improvements in Molecular Prognostic Models for Breast Cancer
Adam A. Margolin,Erhan Bilal,Erich Huang,Erich Huang,Thea Norman,Lars Ottestad,Brigham H. Mecham,Ben Sauerwine,Michael R. Kellen,Lara M. Mangravite,Matthew D. Furia,Matthew D. Furia,Hans Kristian Moen Vollan,Hans Kristian Moen Vollan,Oscar M. Rueda,Justin Guinney,Nicole A. Deflaux,Bruce Hoff,Xavier Schildwachter,Hege G. Russnes,Daehoon Park,Veronica O. Vang,Tyler Pirtle,Lamia Youseff,Craig Citro,Christina Curtis,Vessela N. Kristensen,Joseph L. Hellerstein,Stephen H. Friend,Gustavo Stolovitzky,Samuel Aparicio,Carlos Caldas,Anne Lise Børresen-Dale,Anne Lise Børresen-Dale +33 more
TL;DR: An open challenge to model breast cancer prognosis revealed that collaboration and transparency enhanced the power of prognostic models and formed the basis for a new style of publication peer review.
Journal ArticleDOI
Summary of the DREAM8 Parameter Estimation Challenge: Toward Parameter Identification for Whole-Cell Models
Jonathan R. Karr,Alex H. Williams,Jeremy Zucker,Andreas Raue,Bernhard Steiert,Jens Timmer,Clemens Kreutz,Simon Wilkinson,Brandon A. Allgood,Brian M. Bot,Bruce Hoff,Michael R. Kellen,Markus W. Covert,Gustavo Stolovitzky,Pablo Meyer +14 more
TL;DR: The Dialogue for Reverse Engineering Assessments and Methods (DREAM) 8 Whole-Cell Parameter Estimation Challenge was organized to develop new parameter estimation algorithms for whole-cell models and several valuable lessons were learned toward improving future challenges.
Journal ArticleDOI
Crowdsourced assessment of common genetic contribution to predicting anti-TNF treatment response in rheumatoid arthritis
Solveig K. Sieberts,Zhu Fan,Javier Garcia-Garcia,Eli A. Stahl,Abhishek Pratap,Gaurav Pandey,Dimitrios A. Pappas,Daniel Aguilar,Bernat Anton,Jaume Bonet,Ridvan Eksi,Oriol Fornes,Emre Guney,Hong-Dong Li,Manuel Alejandro Marín,Bharat Panwar,Joan Planas-Iglesias,Daniel Poglayen,Jing Cui,André O. Falcão,Christine Suver,Bruce Hoff,Venkatachalapathy S. K. Balagurusamy,Donna N. Dillenberger,Elias Chaibub Neto,Thea Norman,Tero Aittokallio,Muhammad Ammad-ud-din,Muhammad Ammad-ud-din,Chloé-Agathe Azencott,Victor Bellon,Valentina Boeva,Kerstin Bunte,Kerstin Bunte,Himanshu Chheda,Lu Cheng,Lu Cheng,Lu Cheng,Jukka Corander,Jukka Corander,Michel Dumontier,Anna Goldenberg,Peddinti Gopalacharyulu,Mohsen Hajiloo,Daniel Hidru,Alok Jaiswal,Samuel Kaski,Samuel Kaski,Samuel Kaski,Beyrem Khalfaoui,Suleiman A. Khan,Suleiman A. Khan,Suleiman A. Khan,Eric R. Kramer,Pekka Marttinen,Pekka Marttinen,Aziz M. Mezlini,Bhuvan Molparia,Matti Pirinen,Janna Saarela,Matthias Samwald,Véronique Stoven,Hao Tang,Jing Tang,Ali Torkamani,Jean Phillipe Vert,Bo Wang,Tao Wang,Krister Wennerberg,Nathan E. Wineinger,Guanghua Xiao,Yang Xie,Rae S. M. Yeung,Xiaowei Zhan,Cheng Zhao,Jeff Greenberg,Joel M. Kremer,Kaleb Michaud,Anne Barton,Marieke J H Coenen,Xavier Mariette,Corinne Miceli,Nancy A. Shadick,Michael E. Weinblatt,Niek de Vries,Paul P. Tak,Danielle M. Gerlag,Tom W J Huizinga,Fina A S Kurreeman,Cornelia F Allaart,S. Louis Bridges,Lindsey A. Criswell,Larry W. Moreland,Lars Klareskog,Saedis Saevarsdottir,Leonid Padyukov,Peter K. Gregersen,Stephen H. Friend,Robert M. Plenge,Gustavo Stolovitzky,Baldo Oliva,Yuanfang Guan,Lara M. Mangravite +102 more
TL;DR: Results formally confirm the expectations of the rheumatology community that SNP information does not significantly improve predictive performance relative to standard clinical traits, thereby justifying a refocusing of future efforts on collection of other data.
Journal ArticleDOI
Stratification of amyotrophic lateral sclerosis patients: a crowdsourcing approach
Robert Kueffner,Neta Zach,Maya Bronfeld,Raquel Norel,Nazem Atassi,Venkatachalapathy S. K. Balagurusamy,Barbara Di Camillo,Adriano Chiò,Merit Cudkowicz,Donna N. Dillenberger,Javier Garcia-Garcia,Orla Hardiman,Bruce Hoff,Joshua W. Knight,Melanie Leitner,Guang Li,Lara M. Mangravite,Thea Norman,Liuxia Wang,Jinfeng Xiao,Wen-Chieh Fang,Jian Peng,Chen Yang,Huan-Jui Chang,Gustavo Stolovitzky +24 more
TL;DR: A new method to integrate and analyze patient clusters across methods is proposed, showing a clear pattern of consistent and clinically relevant sub-groups of patients that also enabled the reliable classification of new patients.