C
Catalina Vasilescu
Researcher at University of Bonn
Publications - 8
Citations - 3149
Catalina Vasilescu is an academic researcher from University of Bonn. The author has contributed to research in topics: Genome-wide association study & Biology. The author has an hindex of 7, co-authored 7 publications receiving 3032 citations. Previous affiliations of Catalina Vasilescu include Ludwig Maximilian University of Munich.
Papers
More filters
Journal ArticleDOI
Large recurrent microdeletions associated with schizophrenia
Hreinn Stefansson,Dan Rujescu,Sven Cichon,Olli Pietiläinen,Andres Ingason,Stacy Steinberg,Ragnheidur Fossdal,Engilbert Sigurdsson,Thordur Sigmundsson,Jacobine E. Buizer-Voskamp,Thomas Hansen,Thomas Hansen,Klaus D. Jakobsen,Klaus D. Jakobsen,Pierandrea Muglia,Clyde Francks,Paul M. Matthews,Arnaldur Gylfason,Bjarni V. Halldorsson,Daniel F. Gudbjartsson,Thorgeir E. Thorgeirsson,Asgeir Sigurdsson,Adalbjorg Jonasdottir,Aslaug Jonasdottir,Asgeir Björnsson,Sigurborg Mattiasdottir,Thorarinn Blondal,Magnús Haraldsson,Brynja B. Magnusdottir,Ina Giegling,Hans-Jürgen Möller,Annette M. Hartmann,Kevin V. Shianna,Dongliang Ge,Anna C. Need,Caroline Crombie,Gillian Fraser,Nicholas Walker,Jouko Lönnqvist,Jaana Suvisaari,Annamarie Tuulio-Henriksson,Tiina Paunio,T. Toulopoulou,Elvira Bramon,Marta Di Forti,Robin M. Murray,Mirella Ruggeri,Evangelos Vassos,Sarah Tosato,Muriel Walshe,Tao Li,Tao Li,Catalina Vasilescu,Thomas W. Mühleisen,August G. Wang,Henrik Ullum,Srdjan Djurovic,Ingrid Melle,Jes Olesen,Lambertus A. Kiemeney,Barbara Franke,Chiara Sabatti,Nelson B. Freimer,Jeffrey R. Gulcher,Unnur Thorsteinsdottir,Augustine Kong,Ole A. Andreassen,Roel A. Ophoff,Roel A. Ophoff,Alexander Georgi,Marcella Rietschel,Thomas Werge,Hannes Petursson,David Goldstein,Markus M. Nöthen,Leena Peltonen,Leena Peltonen,David A. Collier,David A. Collier,David St Clair,Kari Stefansson,Kari Stefansson +81 more
TL;DR: In a genome-wide search for CNVs associating with schizophrenia, a population-based sample was used to identify de novo CNVs by analysing 9,878 transmissions from parents to offspring and three deletions significantly associate with schizophrenia and related psychoses in the combined sample.
Journal ArticleDOI
Identification of loci associated with schizophrenia by genome-wide association and follow-up
Michael Conlon O'Donovan,Nicholas John Craddock,Nadine Norton,Hywel Williams,T. Peirce,Valentina Moskvina,Ivan Nikolov,Marian L. Hamshere,Liam S. Carroll,Lyudmila Georgieva,Sarah Dwyer,Peter Holmans,Jonathan Marchini,Chris C. A. Spencer,Bryan Howie,H. T. Leung,Annette M. Hartmann,Hans-Jürgen Möller,Derek W. Morris,Yongyong Shi,Guo Yin Feng,Per Hoffmann,Peter Propping,Catalina Vasilescu,Wolfgang Maier,Marcella Rietschel,Stanley Zammit,Johannes Schumacher,Emma M. Quinn,Thomas G. Schulze,Nigel Williams,Ina Giegling,Nakao Iwata,Masashi Ikeda,Ariel Darvasi,Sagiv Shifman,Lin He,Jubao Duan,Alan R. Sanders,Douglas F. Levinson,Pablo V. Gejman,Nancy G. Buccola,Bryan J. Mowry,Robert Freedman,Farooq Amin,Donald W. Black,Jeremy M. Silverman,William Byerley,C. Robert Cloninger,Sven Cichon,Markus M. Nöthen,Michael Gill,Aiden Corvin,Dan Rujescu,George Kirov,Michael John Owen +55 more
TL;DR: Meta-analysis provided strongest evidence for association around ZNF804A and this strengthened when the affected phenotype including bipolar disorder included bipolar disorder and the overall pattern of replication was unlikely to occur by chance.
Journal ArticleDOI
The DISC locus and schizophrenia: evidence from an association study in a central European sample and from a meta-analysis across different European populations
Johannes Schumacher,Gonzalo Laje,Rami Abou Jamra,Tim Becker,Thomas W. Mühleisen,Catalina Vasilescu,Manuel Mattheisen,Stefan Herms,Per Hoffmann,Axel M. Hillmer,Alexander Georgi,Christine Herold,Thomas G. Schulze,Peter Propping,Marcella Rietschel,Francis J. McMahon,Markus M. Nöthen,Sven Cichon +17 more
TL;DR: The findings point to a complex association between schizophrenia and DISC, including the presence of different risk loci and SNP interplay effects, and the value of homogenous samples in mapping risk genes for schizophrenia in general, and at the DISC locus in particular.
Journal ArticleDOI
Analysis of 10 independent samples provides evidence for association between schizophrenia and a SNP flanking fibroblast growth factor receptor 2.
Michael Conlon O'Donovan,Nadine Norton,Hywel Williams,T. Peirce,Valentina Moskvina,Ivan Nikolov,Marian L. Hamshere,Liam S. Carroll,Lyudmila Georgieva,Sarah Dwyer,Peter Holmans,Jonathan Marchini,Chris C. A. Spencer,Bryan Howie,H. T. Leung,Ina Giegling,Annette M. Hartmann,H.-J. Möller,Derek W. Morris,Yongyong Shi,G. Y. Feng,Peter Hoffmann,Peter Propping,Catalina Vasilescu,Wolfgang Maier,M. Rietschel,Stanley Zammit,Johannes Schumacher,Emma M. Quinn,Thomas G. Schulze,Nakao Iwata,Masashi Ikeda,Ariel Darvasi,Sagiv Shifman,Lin He,Jubao Duan,Alan R. Sanders,Douglas F. Levinson,Rolf Adolfsson,Urban Ösby,Lars Terenius,Erik G. Jönsson,Sven Cichon,Markus M. Nöthen,Michael Gill,Aiden Corvin,Dan Rujescu,Pablo V. Gejman,George Kirov,N. Craddock,Nigel Williams,Michael John Owen,Nancy G. Buccola,Bryan J. Mowry,Robert Freedman,Farooq Amin,Donald W. Black,Jeremy M. Silverman,W. J. Byerley,C. R. Cloninger +59 more
TL;DR: Across all replication samples, the allele at rs17101921 that was associated in the GWAS showed evidence for association independent of the original data (OR 1.17) making this a potential susceptibility gene for schizophrenia.
Journal ArticleDOI
Polymorphisms in SREBF1 and SREBF2, two antipsychotic-activated transcription factors controlling cellular lipogenesis, are associated with schizophrenia in German and Scandinavian samples.
S. Le Hellard,S. Le Hellard,Thomas W. Mühleisen,Srdjan Djurovic,Johan Fernø,Johan Fernø,Z Ouriaghi,Manuel Mattheisen,Catalina Vasilescu,Maria B. Ræder,Maria B. Ræder,Thomas Hansen,Jana Strohmaier,Alexander Georgi,Felix F. Brockschmidt,Ingrid Melle,Igor Nenadic,Heinrich Sauer,Marcella Rietschel,Markus M. Nöthen,Thomas Werge,Ole A. Andreassen,Sven Cichon,Vidar M. Steen,Vidar M. Steen +24 more
TL;DR: The hypothesis that SREBP-controlled cholesterol biosynthesis is involved in the etiology of schizophrenia is strengthened by a HapMap-based association study in a large German sample, which identified association between schizophrenia and five markers in SREBF1 and five marker in S REBF2.