Liam S. Carroll

TL;DR: Meta-analysis provided strongest evidence for association around ZNF804A and this strengthened when the affected phenotype including bipolar disorder included bipolar disorder and the overall pattern of replication was unlikely to occur by chance.

TL;DR: It is shown that copy number variations are likely to be important risk factors for autism and schizophrenia, whereas common single-nucleotide polymorphism alleles have a role in all disorders, and some of the specific genetic loci implicated so far encode proteins that function in synaptic development and plasticity, and therefore may represent a common biological pathway for these disorders.

TL;DR: The allelic association at the ZNF804A locus is now one of the most compelling in schizophrenia to date, and supports the accumulating data suggesting overlapping genetic risk between schizophrenia and bipolar disorder.

TL;DR: This is the first example of passive transfer of an autoimmune peripheral neuropathic pain disorder and demonstrates that CASPR2 has a key role in regulating cell-intrinsic dorsal root ganglion (DRG) neuron excitability.

TL;DR: The yeast two-hybrid system is used to identify proteins that interact with ERBB4, to identify genes and pathways that might contribute to schizophrenia susceptibility and indicates a role for RPTPβ in the modulation of ER BB4 signaling that may in turn provide further support for an important role of neuregulin/ERBB4 signaling in the molecular basis of schizophrenia.