C
Cecile Vicier
Researcher at Aix-Marseille University
Publications - 52
Citations - 873
Cecile Vicier is an academic researcher from Aix-Marseille University. The author has contributed to research in topics: Internal medicine & Medicine. The author has an hindex of 10, co-authored 35 publications receiving 538 citations. Previous affiliations of Cecile Vicier include French Institute of Health and Medical Research & University of Paris-Sud.
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Journal ArticleDOI
Precision medicine for metastatic breast cancer—limitations and solutions
Monica Arnedos,Cecile Vicier,Sherene Loi,Celine Lefebvre,Stefan Michiels,Hervé Bonnefoi,Fabrice Andre +6 more
TL;DR: Limitations and solutions are discussed, which include scaling-up the number of patients screened for identifying a genomic alteration, the clustering of genomic alterations into pathways, and the development of personalized medicine trials.
Journal ArticleDOI
Pervasive chromosomal instability and karyotype order in tumour evolution.
Thomas B.K. Watkins,Emilia L. Lim,Emilia L. Lim,Marina Petkovic,Sergi Elizalde,Nicolai Juul Birkbak,Nicolai Juul Birkbak,Nicolai Juul Birkbak,Gareth A. Wilson,David Allan Moore,Eva Grönroos,Andrew Rowan,Sally M. Dewhurst,Jonas Demeulemeester,Jonas Demeulemeester,Stefan C. Dentro,Stefan C. Dentro,Stefan C. Dentro,Stuart Horswell,Lewis Au,Lewis Au,Kerstin Haase,Mickael Escudero,Rachel Rosenthal,Rachel Rosenthal,Maise Al Bakir,Hang Xu,Kevin Litchfield,Wei-Ting Lu,Thanos P. Mourikis,Michelle Dietzen,Lavinia Spain,Lavinia Spain,George D. Cresswell,Dhruva Biswas,Dhruva Biswas,Philippe Lamy,Iver Nordentoft,Katja Harbst,Francesc Castro-Giner,Francesc Castro-Giner,Lucy R. Yates,Lucy R. Yates,Franco Caramia,Fanny Jaulin,Cecile Vicier,Ian Tomlinson,Priscilla K. Brastianos,Priscilla K. Brastianos,Raymond J. Cho,Boris C. Bastian,Lars Dyrskjøt,Göran Jönsson,Peter Savas,Peter Savas,Sherene Loi,Sherene Loi,Peter J. Campbell,Fabrice Andre,Fabrice Andre,Nicholas M. Luscombe,Nicholas M. Luscombe,Nicholas M. Luscombe,Neeltje Steeghs,Vivianne C. G. Tjan-Heijnen,Zoltan Szallasi,Zoltan Szallasi,Samra Turajlic,Samra Turajlic,Mariam Jamal-Hanjani,Peter Van Loo,Samuel F. Bakhoum,Roland F. Schwarz,Roland F. Schwarz,Nicholas McGranahan,Charles Swanton,Charles Swanton +76 more
TL;DR: Multi-sample phasing and SCNA analysis of 1,421 samples from 394 tumours across 22 tumour types are used to show that continuous chromosomal instability results in pervasive SCNA heterogeneity.
Journal ArticleDOI
Clinical development of mTOR inhibitors in breast cancer
Cecile Vicier,Maria Vittoria Dieci,Monica Arnedos,Monica Arnedos,Suzette Delaloge,Patrice Viens,Fabrice Andre,Fabrice Andre +7 more
TL;DR: Several randomized trials have shown that the use of mTOR inhibitors could improve patient outcome with hormone receptor-positive or human epidermal growth factor receptor-2-positive breast cancer, and new perspectives from these trials are analyzed.
Journal ArticleDOI
Chk1 as a new therapeutic target in triple-negative breast cancer.
Laurence Albiges,Aicha Goubar,Véronique Scott,Cecile Vicier,Celine Lefebvre,Samar Alsafadi,Frédéric Commo,Mahasti Saghatchian,Vladimir Lazar,Philippe Dessen,Suzette Delaloge,Fabrice Andre,Virginie Quidville +12 more
TL;DR: Findings suggest that Chk1 may represent a therapeutic target in TNBC, and provide a rationale to evaluate Chk 1 inhibitors in breast cancer patients.
Journal ArticleDOI
A gene signature to predict high tumor-infiltrating lymphocytes after neoadjuvant chemotherapy and outcome in patients with triple-negative breast cancer
Carmen Criscitiello,Mohamed Amine Bayar,Mohamed Amine Bayar,Giuseppe Curigliano,Fraser Symmans,Christine Desmedt,Hervé Bonnefoi,Bruno Valentin Sinn,Giancarlo Pruneri,Cecile Vicier,Cecile Vicier,Jean-Yves Pierga,Carsten Denkert,Sibylle Loibl,Christos Sotiriou,Stefan Michiels,Stefan Michiels,Fabrice Andre,Fabrice Andre +18 more
TL;DR: A four-gene signature predicts high levels of TILs after anthracycline-containing NACT and outcome in patients with TNBC and adds prognostic information to a clinicopathological model at diagnosis.