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Charles E. Rupprecht

Researcher at Wistar Institute

Publications -  484
Citations -  29552

Charles E. Rupprecht is an academic researcher from Wistar Institute. The author has contributed to research in topics: Rabies & Rabies virus. The author has an hindex of 86, co-authored 475 publications receiving 27058 citations. Previous affiliations of Charles E. Rupprecht include United States Department of Health and Human Services & Global Alliance for Rabies Control.

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The History of Rabies in Trinidad: Epidemiology and Control Measures

TL;DR: The changing epidemiology of rabies in Trinidad is described and cases evaluated towards the design and implementation of more evidence-based prevention and control programs.
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The feasibility of rabies virus-vectored immunocontraception in a mouse model

TL;DR: An initial success of immunocontraception in mice is promising, and the investigation provides insight into the utility of RABV G as a carrier for small peptides and its suitability for vaccine studies.
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A single center, open label study of intradermal administration of an inactivated purified chick embryo cell culture rabies virus vaccine in adults.

TL;DR: A clinical trial was designed to compare the immunogenic and adverse effects of a purified chicken embryo cell (PCEC) RV administered ID or IM, and multi use of 1mL rabies vaccine vials for ID doses of 0.1 was demonstrated to be both safe and inmunogenic.
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Vaccination of free-ranging Pennsylvania raccoons (Procyon lotor) with inactivated rabies vaccine.

TL;DR: Thirty-nine free-ranging raccoons (Procyon lotor) in an endemic rabies area of Pennsylvania (USA) were vaccinated with a single intramuscular inoculation of commercial inactivated rabies virus vaccine, resulting in the death of two of three vaccinates and five of five unvaccinated control raccoon.
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Optimal frequency of rabies vaccination campaigns in Sub-Saharan Africa

TL;DR: If a geographically coordinated campaign could reduce reintroduction, vaccination campaigns every 2 years could effectively manage rabies in both districts and coordinated campaigns may provide monetary savings in addition to public health benefits.