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Charles E. Rupprecht

Researcher at Wistar Institute

Publications -  484
Citations -  29552

Charles E. Rupprecht is an academic researcher from Wistar Institute. The author has contributed to research in topics: Rabies & Rabies virus. The author has an hindex of 86, co-authored 475 publications receiving 27058 citations. Previous affiliations of Charles E. Rupprecht include United States Department of Health and Human Services & Global Alliance for Rabies Control.

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Epidemiology of Human Rabies in the United States, 1980 to 1996

TL;DR: This report includes all laboratory-confirmed cases of human rabies in the United States or its territories from 1980 to 1996 and all of the cases were reported to the Centers for Disease Control and Prevention by health authorities as part of ongoing national surveillance.
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Oral immunization and protection of raccoons (Procyon lotor) with a vaccinia-rabies glycoprotein recombinant virus vaccine.

TL;DR: This work demonstrates the feasibility of a recombinant virus vaccine containing the rabies glycoprotein gene for immunization of raccoons, and possibly other wildlife, to obtain long-term protection against rabies.

Use of a Reduced (4-Dose) Vaccine Schedule for Postexposure Prophylaxis to Prevent Human Rabies

TL;DR: The reduction in doses recommended for PEP was based in part on evidence from rabies virus pathogenesis data, experimental animal work, clinical studies, and epidemiologic surveillance.
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A high-resolution genetic signature of demographic and spatial expansion in epizootic rabies virus

TL;DR: This study demonstrates the combined evolutionary and population dynamic processes characterizing the spread of pathogen after its introduction into a fully susceptible host population and validate the use of coalescent approaches for uncovering even relatively complex population histories.