C
Charles E. Rupprecht
Researcher at Wistar Institute
Publications - 484
Citations - 29552
Charles E. Rupprecht is an academic researcher from Wistar Institute. The author has contributed to research in topics: Rabies & Rabies virus. The author has an hindex of 86, co-authored 475 publications receiving 27058 citations. Previous affiliations of Charles E. Rupprecht include United States Department of Health and Human Services & Global Alliance for Rabies Control.
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Journal ArticleDOI
Response to vaccination with a commercial inactivated rabies vaccine in a captive colony of Brazilian free-tailed bats (Tadarida brasiliensis).
Amy S. Turmelle,Louise C. Allen,Barbara A. Schmidt-French,Felix R. Jackson,Thomas H. Kunz,Gary F. McCracken,Charles E. Rupprecht +6 more
TL;DR: Annual vaccination may maintain immunity against RABV infection in captive colonies of bats and baseline titer significantly predicted humoral response to vaccination.
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In Vivo Efficacy of SYN023, an Anti-Rabies Monoclonal Antibody Cocktail, in Post-Exposure Prophylaxis Animal Models.
TL;DR: In vivo characterization of SYN023 supports its utility in human rabies PEP as an efficacious alternative to RIG products, and reduces neutralizing antibody titers similar to HRIG.
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Historical, current and expected future occurrence of rabies in enzootic regions.
Charles E. Rupprecht,H Bannazadeh Baghi,V J Del Rio Vilas,Andrew D Gibson,Frederic Lohr,F X Meslin,J F R Seetahal,Kate Shervell,Luke Gamble +8 more
TL;DR: The elimination of human rabies mediated via dogs by 2030 in Africa, Asia and the Middle East will not be simple, rapid or inexpensive, but it may be achievable through the use of widely available tools and the application of lessons learned during the course of the 20th century.
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Coronavirus antibodies in bat biologists.
Lauren J. Stockman,Lia M. Haynes,Congrong Miao,Jennifer L Harcourt,Charles E. Rupprecht,Thomas G. Ksiazek,Terri B. Hyde,Alicia M. Fry,Larry J. Anderson +8 more
TL;DR: Serum samples from 90 participants looked for serologic evidence of infection among bat biologists attending an international meeting in the United States and found negative antibodies against inactivated SARS-CoV and against recombinant N proteins of human CoVs, HCoV-229E, H coV-OC43, NL63, and HKU-1.
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Detection of Mokola virus neutralising antibodies in Nigerian dogs.
TL;DR: Three serum samples were seropositive to Mokola virus but all were negative to Lagos bat and Duvenhage viruses, which may explain occasional rabies-like canine mortalities within one year of antirabies vaccination in Nigeria.