C
Charles E. Rupprecht
Researcher at Wistar Institute
Publications - 484
Citations - 29552
Charles E. Rupprecht is an academic researcher from Wistar Institute. The author has contributed to research in topics: Rabies & Rabies virus. The author has an hindex of 86, co-authored 475 publications receiving 27058 citations. Previous affiliations of Charles E. Rupprecht include United States Department of Health and Human Services & Global Alliance for Rabies Control.
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Journal Article
Epidemiology and pathogenicity of African bat lyssaviruses.
Wanda Markotter,C. Van Eeden,Ivan V. Kuzmin,Charles E. Rupprecht,Janusz T. Paweska,R. Swanepoel,Anthony R. Fooks,Claude T. Sabeta,Florence Cliquet,Louis Hendrik Nel +9 more
TL;DR: For Duvenhage virus nucleoprotein nucleotide sequence analysis indicated a very low nucleotide diversity even though isolates were isolated decades apart, and individual isolates of Lagos bat virus were found to differ significantly with respect to nucleop protein gene nucleotide sequences diversity as well as in pathogenicity profiles.
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Concomitant administration of GonaCon™ and rabies vaccine in female dogs (Canis familiaris) in Mexico.
Fernando Vargas-Pino,Verónica Gutiérrez-Cedillo,Erick J. Canales-Vargas,Luis R. Gress-Ortega,Lowell A. Miller,Charles E. Rupprecht,Scott C. Bender,Patricia García-Reyna,Juan Ocampo-López,Dennis Slate +9 more
TL;DR: Future studies that monitor fertility through multiple breeding cycles represent a research need to determine the value of integrating this vaccine into dog rabies management.
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Evolutionary dynamics of rabies viruses highlights the importance of China rabies transmission in Asia.
Sheng-Li Meng,Yan Sun,Xianfu Wu,Jianrong Tang,Ge-Lin Xu,Yongliang Lei,Jie Wu,Jiaxin Yan,Xiao-Ming Yang,Charles E. Rupprecht +9 more
TL;DR: This work examined 200 complete nucleoprotein (N) gene sequences from RABV isolates in the region to explore the possible origin, phylogenetic relationships, and evolutionary dynamics of Asian Rabies viruses (RABV).
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Lagos bat virus virulence in mice inoculated by the peripheral route.
TL;DR: Comparison of amino-acid substitutions among the viral glycoproteins demonstrated significant differences within two antigenic sites between different phylogenetic lineages of LBV.
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Cross-protective and cross-reactive immune responses to recombinant vaccinia viruses expressing full-length lyssavirus glycoprotein genes
TL;DR: It is concluded that a single recombinant poxvirus-vectored vaccine including MOKV and RABV glycoprotein genes, should be a major addition to available rabies biologics and should offer broad protection against all of the lyssaviruses, except WCBV.