C
Charles E. Rupprecht
Researcher at Wistar Institute
Publications - 484
Citations - 29552
Charles E. Rupprecht is an academic researcher from Wistar Institute. The author has contributed to research in topics: Rabies & Rabies virus. The author has an hindex of 86, co-authored 475 publications receiving 27058 citations. Previous affiliations of Charles E. Rupprecht include United States Department of Health and Human Services & Global Alliance for Rabies Control.
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Isolation of Kaeng Khoi virus from dead Chaerephon plicata bats in Cambodia.
Jane C. Osborne,Charles E. Rupprecht,James G. Olson,Thomas G. Ksiazek,Pierre E. Rollin,Michael Niezgoda,Cynthia S. Goldsmith,Ung Sam An,Stuart T. Nichol +8 more
TL;DR: Genetic data, together with earlier serologic data, show that KK viruses represent a distinct group within the genus Orthobunyavirus, and extend the known virus geographic range and document the first KK virus isolation in 30 years.
Journal Article
Rabies surveillance in the United States during 1996.
TL;DR: The number of reported rabid bats decreased 5.8%, with cases reported by 46 of the 48 contiguous states, and Cats continued to be the domestic animal most frequently reported rabid, but reported cases of rabies in cats, cattle, and dogs decreased by 7.6% and 3.7%, respectively.
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Large-scale human exposures to rabid or presumed rabid animals in the United States: 22 cases (1990-1996).
TL;DR: Large-scale exposures most commonly involved a single companion animal and use of an episode-specific algorithm to determine need for postexposure prophylaxis (PEP) may also reduce the number of unnecessary treatments.
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Oral vaccination of raccoons (Procyon lotor) with genetically modified rabies virus vaccines.
Jesse D. Blanton,Joshua S. Self,Michael Niezgoda,Marie-Luise Faber,Bernhard Dietzschold,Charles E. Rupprecht +5 more
TL;DR: The results of this preliminary study suggest that SPBNGAS-GAS provides comparable efficacy to V-RG, and additional studies will be needed to determine the duration of immunity and optimal dosage of SPB NGAS- GAS and to examine its efficacy in other reservoir species.
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Development of combined vaccines for rabies and immunocontraception
TL;DR: All GnRH-carrying rabies viruses induced antibodies against GnRH in immunized mice and protected 100% of the animals after rabies virus challenge, and the recombinant viruses reacted strongly with the serum from a GonaCon-immunized animal.