C
Charles E. Rupprecht
Researcher at Wistar Institute
Publications - 484
Citations - 29552
Charles E. Rupprecht is an academic researcher from Wistar Institute. The author has contributed to research in topics: Rabies & Rabies virus. The author has an hindex of 86, co-authored 475 publications receiving 27058 citations. Previous affiliations of Charles E. Rupprecht include United States Department of Health and Human Services & Global Alliance for Rabies Control.
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Book ChapterDOI
Rabies in Terrestrial Animals
TL;DR: With highly effective methods for the prevention of human rabies, including effective tools for the elimination of rabies in dogs, there is a successful extinction of many unique rabies virus variants through oral vaccination.
Journal ArticleDOI
Evidence for a 4-dose vaccine schedule for human rabies post-exposure prophylaxis in previously non-vaccinated individuals.
Charles E. Rupprecht,Deborah J. Briggs,Catherine M. Brown,Richard Franka,Samuel L. Katz,Harry D Kerr,Susan M. Lett,Robin Levis,Martin I. Meltzer,William Schaffner,Paul R. Cieslak +10 more
TL;DR: Based upon the available evidence, a reduced schedule of cell-culture rabies vaccine, administered on days 0, 3, 7, and 14, given in conjunction with rabies immune globulin, was supported and recommended by the United States Advisory Committee on Immunization Practices.
Journal ArticleDOI
Emerging Pattern of Rabies Deaths and Increased Viral Infectivity
TL;DR: The preponderance of rabies deaths connected with the two uncommon L. noctivagans and P. subflavus bat rabies viruses is best explained by their evolution of increased viral infectivity.
Journal ArticleDOI
Renewed global partnerships and redesigned roadmaps for rabies prevention and control
Tiziana Lembo,Tiziana Lembo,Michaël Attlan,Hervé Bourhy,Sarah Cleaveland,Peter Costa,Katinka de Balogh,Betty Dodet,Anthony R. Fooks,Elly F. Hiby,Fernando Leanes,François-Xavier Meslin,Mary Elizabeth Miranda,Thomas Müller,Louis Hendrik Nel,Charles E. Rupprecht,Noël Tordo,Abbigail J. Tumpey,Alex Wandeler,Deborah J. Briggs +19 more
TL;DR: It is demonstrated that the responsibility of managing rabies falls upon multiple sectors, that a truly integrated approach is the key to rabies elimination, and that considerable progress has been made to this effect.
Journal ArticleDOI
Experimental utility of rabies virus-neutralizing human monoclonal antibodies in post-exposure prophylaxis
Cathleen A. Hanlon,C.A DeMattos,C.C DeMattos,Michael Niezgoda,Douglas C. Hooper,Hilary Koprowski,Abner Louis Notkins,Charles E. Rupprecht +7 more
TL;DR: It is suggested that Mabs may provide a promising alternative to RIG and in hamsters, one Mab resulted in protection that was comparable to human RIG.