C
Charles E. Rupprecht
Researcher at Wistar Institute
Publications - 484
Citations - 29552
Charles E. Rupprecht is an academic researcher from Wistar Institute. The author has contributed to research in topics: Rabies & Rabies virus. The author has an hindex of 86, co-authored 475 publications receiving 27058 citations. Previous affiliations of Charles E. Rupprecht include United States Department of Health and Human Services & Global Alliance for Rabies Control.
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Journal ArticleDOI
Detection of high levels of European bat lyssavirus type-1 viral RNA in the thyroid gland of experimentally-infected Eptesicus fuscus bats.
Anthony R. Fooks,Nicholas Johnson,Thomas Müller,Alfred Voß,Karen L. Mansfield,D. Hicks,Alejandro Núñez,Conrad M. Freuling,L. Neubert,Ingrid Kaipf,Annette Denzinger,Richard Franka,Charles E. Rupprecht +12 more
TL;DR: It is speculated that the infection of the thyroid gland may cause subacute thyroiditis, a transient form of thyroiditis causing hyperthyroidism, resulting in changes in adrenocortical activity that could lead to hormonal dysfunction, thereby distinguishing the clinical presentation of rabies in the rabid host.
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Anatomy of the Cape Cod Oral Rabies Vaccination Program
Timothy P. Algeo,Richard B. Chipman,Brian M. Bjorklund,Monte D. Chandler,Xingtai Wang,Dennis Slate,Charles E. Rupprecht +6 more
TL;DR: Algeo et al. as mentioned in this paper described a local rabies control program and efforts to restore Cape Cod, MA to terrestrial rabies-free status, after a 2004 oral rabies vaccination (ORV) barrier breach following 10 years of rabies free status.
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High prevalence of antibodies against canine adenovirus (CAV) type 2 in domestic dog populations in South Africa precludes the use of CAV-based recombinant rabies vaccines
Nicolette Wright,Felix R. Jackson,Michael Niezgoda,James A. Ellison,Charles E. Rupprecht,Louis Hendrik Nel +5 more
TL;DR: It is demonstrated that pre-existing antibodies against CAV, such as naturally occurs in South African dogs, inhibits the development of neutralizing antibodies against RABV when immunized with a CAV-based rabies recombinant vaccine.
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Use of a single anti-nucleocapsid monoclonal antibody to detect rabies antigen in formalin-fixed, paraffin-embedded tissues
TL;DR: The history and clinical appearance suggest the chronic stage of the disease, from which virus was still recoverable, and it seems probable that cases of PLSD may go unnoticed in this country or are mistaken for such conditions.
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Time series analysis of the impact of oral vaccination on raccoon rabies in West Virginia, 1990-2007.
TL;DR: The results of the model indicate that the effect of the ORV intervention to control raccoon rabies was statistically significant, and ORV should be attempted in other enzootic racoon rabies areas.