C
Chen Wang
Researcher at Mayo Clinic
Publications - 198
Citations - 15466
Chen Wang is an academic researcher from Mayo Clinic. The author has contributed to research in topics: Medicine & Serous fluid. The author has an hindex of 33, co-authored 159 publications receiving 11490 citations. Previous affiliations of Chen Wang include Shanghai Jiao Tong University & University of Science and Technology of China.
Papers
More filters
Journal ArticleDOI
Pooled Clustering of High-Grade Serous Ovarian Cancer Gene Expression Leads to Novel Consensus Subtypes Associated with Survival and Surgical Outcomes.
Chen Wang,Sebastian M. Armasu,Kimberly R. Kalli,Matthew J. Maurer,Ethan P. Heinzen,Gary L. Keeney,William A. Cliby,Ann L. Oberg,Scott H. Kaufmann,Ellen L. Goode +9 more
TL;DR: HGSOC tumors may be categorized into five molecular subtypes that associate with overall survival and the extent of residual disease following debulking surgery, which may have future utility in guiding neoadjuvant treatment decisions for women with HGSOC.
Journal ArticleDOI
Late-onset Alzheimer disease risk variants mark brain regulatory loci
Mariet Allen,Michaela Kachadoorian,Minerva M. Carrasquillo,Aditya V. Karhade,Lester Manly,Jeremy D. Burgess,Chen Wang,Daniel J. Serie,Xue Wang,Joanna Siuda,Joanna Siuda,Fanggeng Zou,High Seng Chai,Curtis S. Younkin,Julia E. Crook,Christopher Medway,Thuy Nguyen,Li Ma,Kimberly G. Malphrus,Sarah Lincoln,Ronald C. Petersen,Neill R. Graff-Radford,Yan W. Asmann,Dennis W. Dickson,Steven G. Younkin,Nilufer Ertekin-Taner +25 more
TL;DR: The results suggest that some LOAD GWAS variants mark brain regulatory loci, nominate genes under regulation by LOAD risk variants, and annotate these variants for their brain regulatory effects.
Journal ArticleDOI
Prognostic gene expression signature for high-grade serous ovarian cancer.
Joshua Millstein,Timothy Budden,Timothy Budden,Ellen L. Goode,Michael S. Anglesio,Aline Talhouk,Maria P. Intermaggio,H.S. Leong,S. Chen,Wafaa Elatre,Blake Gilks,Tayyebeh M. Nazeran,Mila Volchek,Rex C. Bentley,Chen Wang,D.S. Chiu,Stefan Kommoss,S.C.Y. Leung,Janine Senz,Amy Lum,V. Chow,Hanwei Sudderuddin,Robertson Mackenzie,Joshy George,David D.L. Bowtell,Georgia Chenevix-Trench,A. Green,P. Webb,Anna deFazio,D. Gertig,Nadia Traficante,Sian Fereday,S. Moore,J. Hung,K. Harrap,T. Sadkowsky,N. Pandeya,M. Malt,A. Mellon,R. Robertson,T. Vanden Bergh,M. Jones,P. Mackenzie,J. Maidens,K. Nattress,Y.E. Chiew,A. Stenlake,H. Sullivan,B. Alexander,P. Ashover,Scott W. Brown,T. Corrish,Lawrence W. Green,L. Jackman,K. Ferguson,K. Martin,A. Martyn,B. Ranieri,J. White,V. Jayde,P. Mamers,L. Bowes,L. Galletta,David H. Giles,Joy Hendley,Kathryn Alsop,Tiffany M. Schmidt,H. Shirley,C. Ball,C. Young,S. Viduka,Hoa Tran,Sanela Bilic,Lydia Glavinas,Julia Brooks,R. Stuart-Harris,F. Kirsten,J. Rutovitz,P. Clingan,Amy E. Glasgow,A. Proietto,S. Braye,Geoffrey Otton,J. Shannon,Tony Bonaventura,J. Stewart,S. Begbie,M. Friedlander,D. Bell,S. Baron-Hay,a A. Ferrier,G. Gard,D. Nevell,Nick Pavlakis,S. Valmadre,B. Young,C. Camaris,R. Crouch,L. Edwards,Neville F. Hacker,D. Marsden,G. Robertson,P. Beale,Jane Beith,J. Carter,C. Dalrymple,R. Houghton,P. Russell,M. Links,J. Grygiel,J. Hill,A. Brand,Karen Byth,R. Jaworski,Paul R. Harnett,Raghwa Sharma,G. Wain,B. Ward,D. Papadimos,A. Crandon,M. Cummings,Keith Horwood,Andreas Obermair,Lewis Perrin,D. Wyld,J. Nicklin,Margaret Davy,Martin K. Oehler,Chad A. Hall,T. Dodd,T. Healy,K. Pittman,D. Henderson,Judy Miller,J. Pierdes,Penny Blomfield,D. Challis,R. McIntosh,Alan L. Parker,Bruce M. Brown,Robert M. Rome,David W. Allen,Peter Grant,Simon Hyde,R. Laurie,M. Robbie,David L. Healy,Tom Jobling,T. Manolitsas,J. McNealage,Peter Rogers,Beatrice Susil,E. Sumithran,I. Simpson,Kelly-Anne Phillips,Danny Rischin,Stephen B. Fox,Daniel Johnson,Stephen Lade,M. Loughrey,N. O’Callaghan,William K. Murray,Paul Waring,V. Billson,Jan Pyman,Deborah Neesham,Michael C. J. Quinn,C. Underhill,R. Bell,L.F. Ng,R. Blum,Vinod Ganju,Ian Hammond,Y. Leung,Anthony McCartney,Michael D. Buck,Izhak Haviv,David M. Purdie,David C. Whiteman,Nikolajs Zeps,Helen Steed,Jennifer M Koziak,Martin Köbel,Iain A. McNeish,Iain A. McNeish,Teodora Goranova,Darren Ennis,Darren Ennis,Geoff Macintyre,D. Silva De Silva,T. Ramón y Cajal,Jesús García-Donas,S. Hernando Polo,Gustavo C. Rodriguez,Kara L. Cushing-Haugen,Holly R. Harris,Holly R. Harris,Casey S. Greene,Rene A. Zelaya,Sabine Behrens,Renée T. Fortner,Peter Sinn,E. Herpel,E. Herpel,Jenny Lester,Jenny Lester,Jan Lubinski,Oleg Oszurek,A. Toloczko,Cezary Cybulski,Janusz Menkiszak,Celeste Leigh Pearce,Celeste Leigh Pearce,M. C. Pike,M. C. Pike,C. Tseng,Jennifer Alsop,Valerie Rhenius,H. Song,Mercedes Jimenez-Linan,Anna M. Piskorz,A Gentry-Maharaj,Chloe Karpinskyj,Martin Widschwendter,Naveena Singh,Catherine J. Kennedy,Catherine J. Kennedy,P.R. Harnett,P.R. Harnett,Bo Gao,Bo Gao,Sharon E. Johnatty,R. Sayer,J. Boros,J. Boros,Stacey J. Winham,Gary L. Keeney,Scott H. Kaufmann,Melissa C. Larson,H. Luk,Brenda Y. Hernandez,Pamela J. Thompson,L R Wilkens,Michael E. Carney,Britton Trabert,Jolanta Lissowska,L A Brinton,Mark E. Sherman,Clara Bodelon,Samantha Hinsley,Liz-Anne Lewsley,R.M. Glasspool,Susana Banerjee,Euan A. Stronach,Paul Haluska,I.L. Ray-Coquard,Sven Mahner,Boris Winterhoff,DJ Slamon,Douglas A. Levine,Douglas A. Levine,Linda E. Kelemen,Javier Benítez,Jenny Chang-Claude,Jenny Chang-Claude,Jacek Gronwald,A.H. Wu,Usha Menon,M. T. Goodman,Joellen M. Schildkraut,N. Wentzensen,Robert S. Brown,Andrew Berchuck,Simon A. Gayther,María Josefa Mosteiro García,Michelle J. Henderson,Mary Anne Rossing,Mary Anne Rossing,Alicia Beeghly-Fadiel,Peter A. Fasching,Peter A. Fasching,Sandra Orsulic,Sandra Orsulic,Beth Y. Karlan,Beth Y. Karlan,Gottfried E. Konecny,David G. Huntsman,D.D. Bowtell,D.D. Bowtell,James D. Brenton,Jennifer A. Doherty,Paul D.P. Pharoah,Susan J. Ramus +292 more
TL;DR: The OTTA-SPOT (Ovarian Tumor Tissue Analysis consortium - Stratified Prognosis of Ovary Tumours) gene expression signature may improve risk stratification in clinical trials by identifying patients who are least likely to achieve 5-year survival.
Journal ArticleDOI
Epigenome-wide ovarian cancer analysis identifies a methylation profile differentiating clear-cell histology with epigenetic silencing of the HERG K+ channel
Mine S. Cicek,Devin C. Koestler,Brooke L. Fridley,Kimberly R. Kalli,Sebastian M. Armasu,Melissa C. Larson,Chen Wang,Stacey J. Winham,Robert A. Vierkant,David N. Rider,Matthew S. Block,Brandy Klotzle,Gottfried E. Konecny,Boris Winterhoff,Habib Hamidi,Viji Shridhar,Jian-Bing Fan,Daniel W. Visscher,Janet E. Olson,Lynn C. Hartmann,Marina Bibikova,Jeremy Chien,Julie M. Cunningham,Ellen L. Goode +23 more
TL;DR: Results suggest that loss of expression of KCNH2 (HERG) by methylation could be a good prognostic marker, given that overexpression of the potassium (K(+)) channel in clear-cell ovarian cancer family members promotes increased proliferation and results in poor prognosis.
Journal ArticleDOI
Preoperative red cell distribution width and neutrophil-to-lymphocyte ratio predict survival in patients with epithelial ovarian cancer.
TL;DR: Combined RDW and NLR scores stratified patients into low, intermediate, intermediate and high risk groups, especially in patients with high-grade serous ovarian cancer (HGSOC), and high NLR was associated with poor RFS as well.