C
Chris Haley
Researcher at University of Edinburgh
Publications - 427
Citations - 26040
Chris Haley is an academic researcher from University of Edinburgh. The author has contributed to research in topics: Quantitative trait locus & Population. The author has an hindex of 71, co-authored 410 publications receiving 23592 citations. Previous affiliations of Chris Haley include Medical Research Council & The Roslin Institute.
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Journal ArticleDOI
Parent of origin genetic effects on methylation in humans are common and influence complex trait variation
Yanni Zeng,Carmen Amador,Charley Xia,Riccardo E. Marioni,Duncan Sproul,Duncan Sproul,Rosie M. Walker,Stewart W. Morris,Andrew D. Bretherick,Oriol Canela-Xandri,Thibaud Boutin,David W. Clark,Archie Campbell,Konrad Rawlik,Caroline Hayward,Reka Nagy,Albert Tenesa,David J. Porteous,James F. Wilson,Ian J. Deary,Kathryn L. Evans,Andrew M. McIntosh,Pau Navarro,Chris Haley +23 more
TL;DR: A genome-wide scan for POE on DNA methylation in 5,101 individuals and a phenome-wide association analysis using the POE mQTL SNPs identifies a previously unidentified imprinted locus associated with waist circumference provide strong evidence for previously unidentified POE-influenced CpGs at 171 independent loci.
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Genetic diversity in European pigs utilizing amplified fragment length polymorphism markers.
Magali SanCristobal,Claude Chevalet,J. Peleman,Henri C M Heuven,B. Brugmans,M. G. M. van Schriek,R. Joosten,A.P. Rattink,Barbara Harlizius,Martien A. M. Groenen,Y. Amigues,M.-Y. Boscher,George C. Russell,Andy Law,Roberta Davoli,Vincenzo Russo,C. Désautés,L. Alderson,E. Fimland,M. Bagga,Juan Vicente Delgado,Jose Luis Vega-Pla,Amparo Martínez Martínez,Maria Ramos,P. Glodek,J. N. Meyer,Gustavo Gandini,Donato Matassino,K. Siggens,Guillaume Laval,Alan Archibald,David J. Milan,K. Hammond,R. Cardellino,Chris Haley,Graham Plastow +35 more
TL;DR: Results obtained with a set of amplified fragment length polymorphism (AFLP) markers as part of a genetic diversity study of European pig breeds that also utilized microsatellite markers showed that data from AFLP markers can be combined with micros satellite data for measuring genetic diversity.
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A Combined Pathway and Regional Heritability Analysis Indicates NETRIN1 Pathway Is Associated With Major Depressive Disorder
Yanni Zeng,Pau Navarro,Ana Maria Fernandez-Pujals,Lynsey S. Hall,Toni-Kim Clarke,Pippa A. Thomson,Blair H. Smith,Blair H. Smith,Lynne J. Hocking,Lynne J. Hocking,Sandosh Padmanabhan,Sandosh Padmanabhan,Caroline Hayward,Donald J. MacIntyre,Naomi R. Wray,Ian J. Deary,David J. Porteous,Chris Haley,Andrew M. McIntosh +18 more
TL;DR: The NETRIN1 signaling pathway is identified as a candidate pathway for MDD and should be explored in further large population studies and the value of combining multiple methods on multiple GWAS data for the identification of risk pathways forMDD is highlighted.
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QTL affecting morphometric traits and stress response in the gilthead seabream (Sparus aurata).
Kay Boulton,C. Massault,C. Massault,C. Massault,Ross D. Houston,Dirk-Jan de Koning,Dirk-Jan de Koning,Chris Haley,Henk Bovenhuis,Costas Batargias,Adelino V.M. Canario,Giorgios Kotoulas,Costas S. Tsigenopoulos +12 more
TL;DR: Fitting body weight as a covariate for the morphometric traits resulted in three genome-wide significant QTL affecting aspects of body shape independent of overall body size, contributing to understanding the genetic regulation of important economic traits in seabream.
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Estimates of genetic parameters for ovulation rate, prenatal survival and litter size in rabbits from an elliptical selection experiment.
TL;DR: Data from an elliptical selection experiment were used to estimate genetic parameters for components of second parity litter size in rabbits and Genetic variation in prenatal survival appears to be the major cause of genetic variation in litter sizes in the rabbit.