Chris Haley

TL;DR: Evidence is provided that the novel SNP disrupts the binding of the YY1 transcription factor, which raises the possibility that it is the causal variant of the CCKAR gene, and could be utilized as a molecular genetic test for increased feed intake, faster lean growth, and reduced days to market weight in segregating commercial lines.

TL;DR: RHM can be a useful tool to explain some of the ‘missing heritability’ of complex trait variation and is confirmed that RHM can have better power than SSGWAS in detecting causal regions including regions containing crucial ungenotyped variants.

TL;DR: The cis and trans effects for a functional BW QTL on chicken chromosome 4 in breast tissue samples from chickens with contrasting QTL genotypes are identified to demonstrate the potential of genetical genomics.

TL;DR: While stratified GWAS analysis revealed a genome-wide significant locus for male MDD, the lack of independent replication, the equivalent SNP-based heritability estimates and the consistent pattern of genetic correlation with other health-related traits suggests that phenotypic stratification in currently available sample sizes is currently weakly justified.

TL;DR: Genetic analysis of 2,544 British and Irish individuals, including previously unstudied Scottish, Shetlandic and Manx individuals, demonstrates widespread structure across Scotland that echoes past kingdoms, and quantifies the considerable structure that is found on its surrounding isles.