C
Christian Griesinger
Researcher at Max Planck Society
Publications - 449
Citations - 25595
Christian Griesinger is an academic researcher from Max Planck Society. The author has contributed to research in topics: Nuclear magnetic resonance spectroscopy & Residual dipolar coupling. The author has an hindex of 76, co-authored 408 publications receiving 23162 citations. Previous affiliations of Christian Griesinger include University of Göttingen & ETH Zurich.
Papers
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Heteronuclear multidimensional NMR experiments for the structure determination of proteins in solution employing pulsed field gradients
TL;DR: Heteronuclear multidimensional NMR experiments for the structure determination of proteins in solution employing pulsed field gradients using lasers and positron-proton collisions.
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Clean TOCSY for proton spin system identification in macromolecules
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A general enhancement scheme in heteronuclear multidimensional NMR employing pulsed field gradients.
Jürgen Schleucher,M. G. Schwendinger,Michael Sattler,Piet O. Schmidt,O. Schedletzky,Steffen J. Glaser,Ole W. Sørensen,Christian Griesinger +7 more
TL;DR: General pulse sequence elements that achieve sensitivity-enhanced coherence transfer from a heteronucleus to protons of arbitrary multiplicity are introduced and incorporated into heteronuclear correlation experiments, in conjunction with coherence selection by the formation of aheteronuclear gradient echo.
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Release of long-range tertiary interactions potentiates aggregation of natively unstructured α-synuclein
Carlos W. Bertoncini,Young-Sang Jung,Claudio O. Fernández,Wolfgang Hoyer,Christian Griesinger,Thomas M. Jovin,Markus Zweckstetter +6 more
TL;DR: Stabilization of the native, autoinhibitory structure of alphaS constitutes a potential strategy for reducing or inhibiting oligomerization and aggregation in Parkinson's disease.
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Structural Polymorphism of 441-Residue Tau at Single Residue Resolution
Marco D. Mukrasch,Stefan Bibow,Jegannath Korukottu,Sadasivam Jeganathan,Jacek Biernat,Christian Griesinger,Eckhard Mandelkow,Markus Zweckstetter +7 more
TL;DR: The methodology reveals that 441-residue tau is highly dynamic in solution with a distinct domain character and an intricate network of transient long-range contacts important for pathogenic aggregation.