C
Chun Li
Researcher at Case Western Reserve University
Publications - 119
Citations - 7161
Chun Li is an academic researcher from Case Western Reserve University. The author has contributed to research in topics: Genome-wide association study & Breast cancer. The author has an hindex of 44, co-authored 118 publications receiving 6596 citations. Previous affiliations of Chun Li include Vanderbilt University & Mayo Clinic.
Papers
More filters
Journal ArticleDOI
Genetic determinants of response to warfarin during initial anticoagulation.
Ute I. Schwarz,Marylyn D. Ritchie,Yuki Bradford,Chun Li,Scott M. Dudek,Amy Frye-Anderson,Richard B. Kim,Dan M. Roden,C. Michael Stein +8 more
TL;DR: Initial variability in the INR response to warfarin was more strongly associated with genetic variability inThe pharmacologic target of warfarIn, VKORC1, than with CYP2C9, and both of these genotypes had a significant influence on the required warfarins after the first 2 weeks of therapy.
Journal ArticleDOI
Genome-wide association study identifies a new breast cancer susceptibility locus at 6q25.1
Wei Zheng,Jirong Long,Yu-Tang Gao,Chun Li,Ying Zheng,Yong Bin Xiang,Wanqing Wen,Shawn Levy,Sandra L. Deming,Jonathan L. Haines,Kai Gu,Alecia M. Fair,Qiuyin Cai,Wei Lu,Xiao-Ou Shu +14 more
TL;DR: Wang et al. as mentioned in this paper carried out a genome-wide association study among Chinese women to identify risk variants for breast cancer and found strong and consistent association with breast cancer across all three stages.
Journal ArticleDOI
Meta-analysis identifies common variants associated with body mass index in east Asians
Wanqing Wen,Yoon Shin Cho,Wei Zheng,Rajkumar Dorajoo,Rajkumar Dorajoo,Norihiro Kato,Lu Qi,Chien Hsiun Chen,Chien Hsiun Chen,Ryan J. Delahanty,Yukinori Okada,Yasuharu Tabara,Dongfeng Gu,Dingliang Zhu,Christopher A. Haiman,Zengnan Mo,Yu Tang Gao,Seang-Mei Saw,Min Jin Go,Fumihiko Takeuchi,Li Ching Chang,Yoshihiro Kokubo,Jun Liang,Mei Hao,Loic Le Marchand,Yi Zhang,Yanling Hu,Tien Yin Wong,Tien Yin Wong,Jirong Long,Bok Ghee Han,Michiaki Kubo,Ken Yamamoto,Mei Hsin Su,Tetsuro Miki,Brian E. Henderson,Huai-Dong Song,Aihua Tan,Jiang He,Daniel P.K. Ng,Qiuyin Cai,Tatsuhiko Tsunoda,Fuu Jen Tsai,Naoharu Iwai,Gary K. Chen,Jiajun Shi,Jianfeng Xu,Xueling Sim,Yong-Bing Xiang,Shiro Maeda,Rick Twee-Hee Ong,Rick Twee-Hee Ong,Chun Li,Yusuke Nakamura,Tin Aung,Tin Aung,Naoyuki Kamatani,Jianjun Liu,Wei Lu,Mitsuhiro Yokota,Mitsuhiro Yokota,Mark Seielstad,Mark Seielstad,Cathy S.J. Fann,Cathy S.J. Fann,Jer-Yuarn Wu,Jer-Yuarn Wu,Jong-Young Lee,Frank B. Hu,Toshihiro Tanaka,E. Shyong Tai,Xiao-Ou Shu +71 more
TL;DR: A meta-analysis of associations between BMI and approximately 2.4 million SNPs in 27,715 east Asians and three additional loci nearly reached the genome-wide significance threshold may shed light on new pathways involved in obesity and demonstrate the value of conducting genetic studies in non-European populations.
Journal ArticleDOI
Allelic heterogeneity at the serotonin transporter locus (SLC6A4) confers susceptibility to autism and rigid-compulsive behaviors
James S. Sutcliffe,Ryan J. Delahanty,Harish C. Prasad,Jacob L. McCauley,Qiao Han,Lan Jiang,Chun Li,Susan E. Folstein,Randy D. Blakely +8 more
TL;DR: From 120 families, most contributing to linkage at 17q11.2, it is hypothesized that preferential transmission of multiple alleles does explain the observed linkage and strong support is provided for a collection of multiple, often rare, alleles at SLC6A4 as imposing risk of autism.
Journal ArticleDOI
Genetic Variation Near the Hepatocyte Nuclear Factor-4α Gene Predicts Susceptibility to Type 2 Diabetes
Kaisa Silander,Karen L. Mohlke,Laura J. Scott,Erin C. Peck,Pablo Hollstein,Andrew D. Skol,Anne U. Jackson,Panagiotis Deloukas,Sarah E. Hunt,George Stavrides,Peter S. Chines,Michael R. Erdos,Narisu Narisu,Karen N. Conneely,Chun Li,Chun Li,Tasha E. Fingerlin,Sharanjeet K. Dhanjal,Timo T. Valle,Richard N. Bergman,Jaakko Tuomilehto,Jaakko Tuomilehto,Richard M. Watanabe,Michael Boehnke,Francis S. Collins +24 more
TL;DR: The results and the independent observation of association of SNPs near the P2 promoter with diabetes in a separate study population of Ashkenazi Jewish origin suggests that variant(s) located near or within HNF4A increases susceptibility to type 2 diabetes.