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Craig A. Bonnington

Researcher at Mahidol University

Publications -  10
Citations -  447

Craig A. Bonnington is an academic researcher from Mahidol University. The author has contributed to research in topics: Malaria & Medicine. The author has an hindex of 4, co-authored 4 publications receiving 303 citations.

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Association of mutations in the Plasmodium falciparum Kelch13 gene (Pf3D7_1343700) with parasite clearance rates after artemisinin-based treatments : a WWARN individual patient data meta-analysis

TL;DR: An individual patient data meta-analysis of the associations between parasite clearance half-life (PC1/2) and pfk13 genotype based on a large set of individual patient records from Asia and Africa demonstrates that 15 additional pfK13 alleles are associated strongly with the slow-clearing phenotype in Southeast Asia.
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Effect of generalised access to early diagnosis and treatment and targeted mass drug administration on Plasmodium falciparum malaria in Eastern Myanmar: an observational study of a regional elimination programme

TL;DR: Providing early diagnosis and effective treatment substantially decreased village-level incidence of artemisinin-resistant P falciparum malaria in hard-to-reach, politically sensitive regions of eastern Myanmar.
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The role of early detection and treatment in malaria elimination.

TL;DR: Implementing large-scale, high-coverage, community-based early diagnosis and treatment through MPs requires few technological innovations but relies on a very well structured organization able to train, supervise and supply MPs, to monitor activity and to perform strict malaria surveillance.
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Plasmodium falciparum Kelch 13 mutations and treatment response in patients in Hpa-Pun District, Northern Kayin State, Myanmar.

TL;DR: This study provides evidence of artemisinin resistance in a remote part of eastern Myanmar, where the prevalence of k13 mutations as well as allele diversity varies considerably across short distances, presumably because of historical patterns of art Artemisinin use and population movements.