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David Qixiang Chen

Researcher at University of Toronto

Publications -  25
Citations -  1979

David Qixiang Chen is an academic researcher from University of Toronto. The author has contributed to research in topics: Tractography & Diffusion MRI. The author has an hindex of 17, co-authored 25 publications receiving 1510 citations. Previous affiliations of David Qixiang Chen include University Health Network & St. Jude Children's Research Hospital.

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Journal ArticleDOI

The challenge of mapping the human connectome based on diffusion tractography

Klaus H. Maier-Hein, +76 more
TL;DR: The encouraging finding that most state-of-the-art algorithms produce tractograms containing 90% of the ground truth bundles (to at least some extent) is reported, however, the same tractograms contain many more invalid than valid bundles, and half of these invalid bundles occur systematically across research groups.
Journal ArticleDOI

Sensorimotor and Pain Modulation Brain Abnormalities in Trigeminal Neuralgia: A Paroxysmal, Sensory-Triggered Neuropathic Pain.

TL;DR: TN is associated with GM abnormalities in areas involved in pain perception, pain modulation and motor function, which may reflect increased nociceptive input to the brain, an impaired descending modulation system that does not adequately inhibit pain, and increased motor output to control facial movements to limit pain attacks.
Journal ArticleDOI

In vivo visualization of cranial nerve pathways in humans using diffusion-based tractography.

TL;DR: Detailed assessment of anatomy and the ability of overlaying the tracts onto anatomic magnetic resonance imaging scans is essential, particularly in the posterior fossa, to ensure that the tracts have been reconstructed with anatomic fidelity.
Posted ContentDOI

Tractography-based connectomes are dominated by false-positive connections

Klaus H. Maier-Hein, +76 more
- 07 Nov 2016 - 
TL;DR: The results demonstrate fundamental ambiguities inherent to tract reconstruction methods based on diffusion orientation information, with critical consequences for the approach of diffusion tractography in particular and human connectivity studies in general.