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David R. Gies

Researcher at Regeneron

Publications -  8
Citations -  2896

David R. Gies is an academic researcher from Regeneron. The author has contributed to research in topics: Receptor tyrosine kinase & Neuromuscular junction. The author has an hindex of 7, co-authored 8 publications receiving 2824 citations.

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Agrin Acts via a MuSK Receptor Complex

TL;DR: It is demonstrated that agrin acts via a receptor complex that includes MuSK as well as a myotube-specific accessory component, which is a receptor tyrosine kinase localized to the motor endplate.
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Mammalian neurotrophin-4: structure, chromosomal localization, tissue distribution, and receptor specificity.

TL;DR: A neurotrophin is isolated from both human and rat genomic DNA that appears to represent the mammalian counterpart of Xenopus/viper NT-4, which has many unusual features compared to the previously identified neurotrophins and is less conserved evolutionarily than the other neurotrophs.
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Alternative forms of rat TrkC with different functional capabilities

TL;DR: This paper identified transcripts encoding several different forms of rat TrkC, a member of the Trk family of receptor tyrosine kinases that serves as a receptor for neurotrophin-3.