Didier Ngabo

TL;DR: This paper presents sequence data and analysis of 142 EBOV samples collected during the period March to October 2015 and shows that real-time genomic surveillance is possible in resource-limited settings and can be established rapidly to monitor outbreaks.

TL;DR: The objectives of the trial were to test the feasibility and acceptability of an emergency trial in the context of a large Ebola outbreak, and to collect data on the safety and effectiveness of favipiravir in reducing mortality and viral load in patients with EVD.

TL;DR: Deep sequencing of 179 patient samples processed by the European Mobile Laboratory, the first diagnostics unit to be deployed to the epicentre of the outbreak in Guinea, reveals an epidemiological and evolutionary history of the epidemic from March 2014 to January 2015, providing an unprecedented window into the evolution of an ongoing viral haemorrhagic fever outbreak.

TL;DR: EVD patients at the time of admission to the Ebola Treatment Center in Guinea, and longitudinally until discharge or death are evaluated, and an immune signature that is unique in EVD fatalities is identified through the use of multiparametric flow cytometry.

TL;DR: Characterise optimal infection dosage inducing upper respiratory tract (UTR) viral shedding, progression time of viral shed, and pathology in ferrets and finally provide evidence for protection after re-challenge in ferret model of SARS-CoV-2.