E
E De Braekeleer
Researcher at University of Western Brittany
Publications - 5
Citations - 834
E De Braekeleer is an academic researcher from University of Western Brittany. The author has contributed to research in topics: ABL & Acute leukemia. The author has an hindex of 5, co-authored 5 publications receiving 770 citations. Previous affiliations of E De Braekeleer include French Institute of Health and Medical Research.
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Journal ArticleDOI
The MLL recombinome of acute leukemias in 2013
Claus Meyer,Julia Hofmann,Thomas Burmeister,Daniela Gröger,T S Park,Mariana Emerenciano,M. Pombo De Oliveira,Aline Renneville,Patrick Villarese,Elizabeth Macintyre,Hélène Cavé,Emmanuelle Clappier,K. Mass-Malo,Jan Zuna,Jan Trka,E De Braekeleer,M. De Braekeleer,S H Oh,Grigory Tsaur,L Fechina,V H J van der Velden,J J M van Dongen,Eric Delabesse,Renata Binato,Mara Silva,AM Kustanovich,Olga V. Aleinikova,Marian H. Harris,T Lund-Aho,Vesa Juvonen,Olaf Heidenreich,Josef Vormoor,William W.L. Choi,Marie Jarošová,A. Kolenova,Clara Bueno,Pablo Menendez,S. Wehner,Cornelia Eckert,Pascaline Talmant,Sylvie Tondeur,Eric Lippert,E. Launay,Catherine Henry,Paola Ballerini,H. Lapillone,Mary Callanan,Jean Michel Cayuela,Charles Herbaux,Giovanni Cazzaniga,P. M. Kakadiya,Stefan K. Bohlander,Martina Ahlmann,Jong Rak Choi,Paula Gameiro,Dongsoon Lee,Juergen Krauter,Pascale Cornillet-Lefebvre,G te Kronnie,Beat W. Schäfer,S. Kubetzko,Cristina N. Alonso,U. Zur Stadt,Rosemary Sutton,N. C. Venn,Shai Izraeli,Luba Trakhtenbrot,H. O. Madsen,P. Archer,Jeremy Hancock,Nuno Cerveira,Manuel R. Teixeira,L Lo Nigro,Anja Möricke,Martin Stanulla,Martin Schrappe,Lukasz Sedek,Tomasz Szczepański,Christian M. Zwaan,Eva A. Coenen,M.M. van den Heuvel-Eibrink,Sabine Strehl,Michael Dworzak,Renate Panzer-Grümayer,Theodor Dingermann,Thomas Klingebiel,Rolf Marschalek +86 more
TL;DR: Long-distance inverse-polymerase chain reaction was used to characterize the chromosomal rearrangement of individual acute leukemia patients and revealed a total of 121 different MLL rearrangements, of which 79 TPGs are now characterized at the molecular level.
Journal ArticleDOI
New insights to the MLL recombinome of acute leukemias
Christian Meyer,Eric Kowarz,Julia Hofmann,Aline Renneville,Jan Zuna,Jan Trka,R. Ben Abdelali,Elizabeth Macintyre,E De Braekeleer,E De Braekeleer,M. De Braekeleer,M. De Braekeleer,Eric Delabesse,M. P. de Oliveira,Hélène Cavé,Emmanuelle Clappier,J J M van Dongen,Brian V. Balgobind,M M van den Heuvel-Eibrink,H B Beverloo,Renate Panzer-Grümayer,Andrea Teigler-Schlegel,Jochen Harbott,Eigil Kjeldsen,Susanne Schnittger,Ulrike Koehl,Bernd Gruhn,Olaf Heidenreich,Li Chong Chan,Sze-Fai Yip,Martin Krzywinski,C Eckert,Anja Möricke,Martin Schrappe,Cristina N. Alonso,Beat W. Schäfer,Jürgen Krauter,Dean A. Lee,U zur Stadt,G te Kronnie,Rosemary Sutton,Shai Izraeli,L. Trakhtenbrot,L. Trakhtenbrot,L Lo Nigro,Grigory Tsaur,Larisa Fechina,Tomasz Szczepański,Sabine Strehl,D. Ilencikova,Mara Molkentin,Thomas Burmeister,Theodor Dingermann,T. Klingebiel,Rolf Marschalek +54 more
TL;DR: In this paper, the distribution of MLL breakpoints for clinical subtypes (acute lymphoblastic leukemia, acute myeloid leukemia, pediatric and adult) and fused translocation partner genes (TPGs) were presented, including novel MLL fusion genes.
Journal ArticleDOI
A new partner gene fused to ABL1 in a t(1;9)(q24;q34)-associated B-cell acute lymphoblastic leukemia.
E De Braekeleer,Nathalie Douet-Guilbert,M-J Le Bris,Christian Berthou,Frédéric Morel,M. De Braekeleer +5 more
TL;DR: A new partner gene fused to ABL1 in a t(1;9)(q24;q34)-associated B-cell acute lymphoblastic leukemia is reported to have cytotoxicity-like properties.
Journal ArticleDOI
Molecular characterization of deletions of the long arm of chromosome 5 (del(5q)) in 94 MDS/AML patients.
Nathalie Douet-Guilbert,Nathalie Douet-Guilbert,E De Braekeleer,E De Braekeleer,Audrey Basinko,Audrey Basinko,Angèle Herry,Nadia Guéganic,Nadia Guéganic,Clément Bovo,Clément Bovo,K Trillet,A Dos Santos,M.-J. Le Bris,Frédéric Morel,Frédéric Morel,Jean-Richard Eveillard,Christian Berthou,M. De Braekeleer,M. De Braekeleer +19 more
TL;DR: Molecular characterization of deletions of the long arm of chromosome 5 (del(5q)) in 94 MDS/AML patients shows clear trends in prognosis and progression in both MDS and AML patients.
Journal ArticleDOI
Acute lymphoblastic leukemia associated with RCSD1-ABL1 novel fusion gene has a distinct gene expression profile from BCR-ABL1 fusion.
E De Braekeleer,E De Braekeleer,Nathalie Douet-Guilbert,Nathalie Douet-Guilbert,P Guardiola,David W. Rowe,Satu Mustjoki,Adriana Zamecnikova,S Al Bahar,G Jaramillo,Christian Berthou,Nick Bown,Kimmo Porkka,C Ochoa,M. De Braekeleer,M. De Braekeleer +15 more
TL;DR: Acute lymphoblastic leukemia associated with RCSD1–ABL1 novel fusion gene has a distinct gene expression profile from BCR–ABl1 fusion.