scispace - formally typeset
E

Edson X. Albuquerque

Researcher at University of Maryland, Baltimore

Publications -  268
Citations -  18565

Edson X. Albuquerque is an academic researcher from University of Maryland, Baltimore. The author has contributed to research in topics: Nicotinic agonist & Acetylcholine. The author has an hindex of 69, co-authored 268 publications receiving 17395 citations. Previous affiliations of Edson X. Albuquerque include Federal University of Rio de Janeiro & National Institute on Drug Abuse.

Papers
More filters
Journal Article

Interactions of gephyrotoxin with the acetylcholine receptor-ionic channel complex. II. Enhancement of desensitization.

C Souccar, +4 more
- 01 May 1984 - 
TL;DR: Results of electrophysiological and binding studies indicate that GyTX not only blocks the open channel of the AChR but also enhances desensitization of the acetylcholine receptor-channel (AChR) complex by increasing receptor affinity for agonists.
Journal Article

Kinetics of interaction of batrachotoxin and tetrodotoxin on rat diaphragm muscle.

Edson X. Albuquerque, +3 more
- 01 Jan 1976 - 
TL;DR: The results suggest that TTX and BTX react with different sites along the same sodium channel, but that procaine and lidocaine probably interfere with the binding of BTX to its receptor site.
Journal Article

The Ionic Channel of the Acetylcholine Receptor: Regulation by Sites Outside and Inside the Cell Membrane Which Are Sensitive to Quaternary Ligands

L. G. Aguayo, +3 more
- 01 Sep 1981 - 
TL;DR: The results indicate that sites controlling the ionic channel of the acetylcholine receptor from the external surface may be significantly different from sites on the internal surface, even though both sites do interact with certain quaternary amines.
Journal ArticleDOI

Conductance properties of GABA-activated chloride currents recorded from cultured hippocampal neurons

Charles N. Allen, +1 more
- 28 Apr 1987 - 
TL;DR: The conductance characteristics of gamma-aminobutyric acid-activated single channel currents from cultured hippocampal neurons were examined using patch clamp techniques and demonstrate that cultured hippocampusal neurons have channel conductances which have characteristics different from those of adult neurons.
Journal ArticleDOI

Spatial learning impairment in prepubertal guinea pigs prenatally exposed to the organophosphorus pesticide chlorpyrifos: Toxicological implications.

Jacek Mamczarz, +8 more
- 01 Sep 2016 - 
TL;DR: The results presented here reveal that the guinea pig is a valuable animal model for preclinical assessment of the developmental neurotoxicity of OP pesticides, and lays the groundwork for future studies aimed at identifying therapeutic interventions to treat and/or prevent the neurotoxic effects of CPF in the developing brain.