E
Edward F. Srour
Researcher at Indiana University
Publications - 204
Citations - 10614
Edward F. Srour is an academic researcher from Indiana University. The author has contributed to research in topics: Stem cell & Haematopoiesis. The author has an hindex of 51, co-authored 202 publications receiving 9991 citations. Previous affiliations of Edward F. Srour include Indiana University – Purdue University Indianapolis & University of New Mexico.
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The 30/35 kDa chymotryptic fragment of fibronectin enhances retroviral-mediated gene transfer in purified chronic myelogenous leukemia bone marrow progenitors.
TL;DR: The results demonstrate the feasibility of transducing normal CML primitive HPC, and illustrate the potential clinical use of FN in the setting of gene therapy for CML, as well as other diseases.
Journal Article
A retroviral vector expressing human interferon gamma upregulates MHC antigen expression in human breast cancer and leukemia cell lines.
TL;DR: It is suggested that expression of interferon gamma in Breast cancer cells may lead to increased recognition of breast cancer cells by the host immune system and further development of this approach to cancer immunotherapy is warranted.
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A novel role for thrombopoietin in regulating osteoclast development in humans and mice.
Monique Bethel,Calvin L. T. Barnes,Amanda F. Taylor,Ying Hua Cheng,Brahmananda R. Chitteti,Mark C. Horowitz,Angela Bruzzaniti,Angela Bruzzaniti,Edward F. Srour,Melissa A. Kacena,Melissa A. Kacena +10 more
TL;DR: In this article, the role of the main megakaryocyte growth factor, thrombopoietin (TPO), on osteoclast formation and bone resorption was examined.
Journal Article
Activated leukocyte cell adhesion molecule (ALCAM or CD166) modulates bone phenotype and hematopoiesis.
R. A. Hooker,B. R. Chitteti,P. H. Egan,Yinghua Cheng,Evan R. Himes,Tomas E. Meijome,Edward F. Srour,Robyn K. Fuchs,Melissa A. Kacena +8 more
TL;DR: Overall, CD166-/- mice displayed modestly elevated trabecular bone volume fraction with increased OB numbers and deposition of osteoid, and increased OB differentiation in vitro, possibly suggesting more mature OB are secreting more osteoid.
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Absence of Cardiomyocyte Differentiation Following Transplantation of Adult Cardiac-Resident Sca-1+ Cells Into Infarcted Mouse Hearts.
Mark H. Soonpaa,Pascal J. Lafontant,Sean Reuter,John A. Scherschel,Edward F. Srour,Marc Michael Zaruba,Michael Rubart-von der Lohe,Loren J. Field +7 more
TL;DR: Monitoring for cardiomyogenic differentiation in isolated adult cardiac-resident Sca-1+ cells was engrafted into infarcted hearts and revealed that at least a portion of the Sca–1+ donor cells express vimentin, as evidenced by the presence of EGFP fluorescence.