E
Edward F. Srour
Researcher at Indiana University
Publications - 204
Citations - 10614
Edward F. Srour is an academic researcher from Indiana University. The author has contributed to research in topics: Stem cell & Haematopoiesis. The author has an hindex of 51, co-authored 202 publications receiving 9991 citations. Previous affiliations of Edward F. Srour include Indiana University – Purdue University Indianapolis & University of New Mexico.
Papers
More filters
Journal ArticleDOI
Regulation of murine hematopoietic stem cell quiescence by Dmtf1.
TL;DR: It is demonstrated that Dmtf1 regulates HSC function under both steady-state and stress conditions, and this results implicate DMTf1 in the regulation of HSCfunction through novel cell cycle-regulatory mechanisms.
Journal ArticleDOI
Preferential sequestration in vitro of BCR/ABL negative hematopoietic progenitor cells among cytokine nonresponsive CML marrow CD34+ cells
TL;DR: These studies confirm the feasibility of employing negative hematopoietic regulators to augment the sequestration of normal HPC among the cytokine nonresponsive fraction of CD34+ cells, an approach that may be clinically feasible for autotransplantation.
Journal ArticleDOI
Sca-1 expression is associated with decreased cardiomyogenic differentiation potential of skeletal muscle-derived adult primitive cells
Ewa K. Zuba-Surma,Ahmed Abdel-Latif,Jamie Case,Sumit Tiwari,Greg Hunt,Magda Kucia,Robert J Vincent,Smita Ranjan,Mariusz Z. Ratajczak,Edward F. Srour,Roberto Bolli,Buddhadeb Dawn +11 more
TL;DR: It is concluded that SM- cells are inherently predisposed to undergo cardiac differentiation and are enriched in markers of pluripotency.
Journal ArticleDOI
In vitro clonal analysis of murine pluripotent stem cells isolated from skeletal muscle and adipose stromal cells.
TL;DR: These data demonstrate that phenotypically defined PSCs remain functionally heterogeneous at the single-cell level and illustrate that morphologic lineage commitment may be independent of exclusive expression and/or loss of associated lineage specific genes.
Journal ArticleDOI
Modulation of hematopoietic progenitor cell fate in vitro by varying collagen oligomer matrix stiffness in the presence or absence of osteoblasts.
TL;DR: Biophysical features of collagen oligomer matrices, specifically fibril density-induced modulation of matrix stiffness, provide important guidance cues in terms of LSK expansion and differentiation and therefore maintenance of progenitor cell function.