E
Edward F. Srour
Researcher at Indiana University
Publications - 204
Citations - 10614
Edward F. Srour is an academic researcher from Indiana University. The author has contributed to research in topics: Stem cell & Haematopoiesis. The author has an hindex of 51, co-authored 202 publications receiving 9991 citations. Previous affiliations of Edward F. Srour include Indiana University – Purdue University Indianapolis & University of New Mexico.
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Journal ArticleDOI
Absence of the Rho GTPase Activating Protein p190-B Enhances Long Term Hematopoietic Stem Cell Engraftment
Haiming Xu,Hartmut Geiger,Kathleen Szczur,Deidra Deira,Yi Zheng,Jeffrey Settleman,Edward F. Srour,David R. Williams,Marie-Dominique Filippi +8 more
TL;DR: In this paper, the role of small Rho GTPases in HSC/P engraftment was investigated, and it was shown that p190-B deficiency may preserve the repopulating capacity of HSC during ex vivo cytokine-induced culture.
C-Mpl Is Expressed on Osteoblasts and Osteoclasts and Is Important in Regulating Skeletal Homeostasis
Tomas E. Meijome,Jenna T. Baughman,R. Adam Hooker,Ying Hua Cheng,Wendy A. Ciovacco,Wendy A. Ciovacco,Sanjeev M. Balamohan,Trishya L. Srinivasan,Brahmananda R. Chitteti,Pierre P. Eleniste,Mark C. Horowitz,Edward F. Srour,Angela Bruzzaniti,Robyn K. Fuchs,Melissa A. Kacena,Melissa A. Kacena +15 more
TL;DR: New findings for the role of MKs and c‐Mpl expression in bone are provided and may provide insight into the homeostatic regulation of bone mass as well as bone loss diseases such as osteoporosis.
Journal ArticleDOI
Human thymic stroma supports human natural killer (NK) cell development from immature progenitors.
TL;DR: The data indicate that NK cells can be obtained in vitro by coculture of immature hematopoietic progenitors with thymic stromal cells and that IL2 appears to strongly favor their development in the absence ofStromal contact.
Posted ContentDOI
The kidney protects against sepsis by enhancing the systemic release of Uromodulin to stimulate macrophage function
Kaice A. LaFavers,Chadi A. Hage,Varun Gaur,Radmila Micanovic,Takashi Hato,Shehnaz Khan,Seth Winfree,Simit Doshi,Ranjani N. Moorthi,Homer L. Twigg,Xue-Ru Wu,Pierre C. Dagher,Edward F. Srour,Tarek M. El-Achkar +13 more
TL;DR: In this paper, Uromodulin (Tamm-Horsfall protein, THP) is a kidney-derived protein bidirectionally released in the urine and circulation, and the authors show that circulating THP increases in experimental murine sepsis without severe acute kidney injury through basolateral shifting of its release within the kidney medulla.
Journal ArticleDOI
UNIT 7.3 Differential Staining of DNA and RNA
TL;DR: This unit presents two protocols for differential staining, one using the metachromatic dye acridine orange (AO) and the other a combination of pyronin Y (PY) and Hoechst 33342.