E
Edward F. Srour
Researcher at Indiana University
Publications - 204
Citations - 10614
Edward F. Srour is an academic researcher from Indiana University. The author has contributed to research in topics: Stem cell & Haematopoiesis. The author has an hindex of 51, co-authored 202 publications receiving 9991 citations. Previous affiliations of Edward F. Srour include Indiana University – Purdue University Indianapolis & University of New Mexico.
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Journal ArticleDOI
Modulation of in vitro proliferation kinetics and primitive hematopoietic potential of individual human CD34+CD38-/lo cells in G0.
Edward F. Srour,X. Tong,Ki Woong Sung,P. Artur Plett,Susan Rice,Joanne Daggy,Constantin T. Yiannoutsos,Rafat Abonour,Christie M. Orschell +8 more
TL;DR: Results suggest that although exit from quiescence and commitment to proliferation might be stochastic, kinetics of proliferation, and possibly fate of primitive HPCs, might be modulated by extrinsic factors.
Journal ArticleDOI
Delayed Targeting of Cytokine-Nonresponsive Human Bone Marrow CD34+ Cells With Retrovirus-Mediated Gene Transfer Enhances Transduction Efficiency and Long-Term Expression of Transduced Genes
Ponnazhagan Veena,C. M. Traycoff,David R. Williams,Jon McMahel,Susan Rice,K Cornetta,Edward F. Srour +6 more
TL;DR: It is demonstrated that prolonged stimulation of primitive HPCs is essential for achieving efficient RMGT into cells capable of sustaining long-term in vitro hematopoiesis and may have significant implications for the development of clinical gene therapy protocols.
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Muscle-derived CD45-SCA-1+c-kit- progenitor cells give rise to skeletal muscle myotubes in vitro.
TL;DR: It is concluded that murine skeletal muscle possesses two populations of progenitor cells that can be directly isolated and one population expressing the phenotype S+CD34− may contain satellite cells, whereas the S+ CD34+ population is devoid of satellite cell markers.
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Skeletal muscle-derived progenitor cells exhibit neural competence.
TL;DR: It is demonstrated that phenotypically homogenous skeletal muscle progenitor cells defined as Lin−CD45−CD117−CD90+ cells express neural stem cell markers and are responsive to neural induction signals.
Journal ArticleDOI
Nonmarrow hematopoiesis occurs in a hyaluronic-acid-rich node and duct system in mice.
Sunhee Hwang,Seung Joon Lee,Sang H. Park,Brahmananda R. Chitteti,Edward F. Srour,Scott Cooper,Giao Hangoc,Hal E. Broxmeyer,Byoung S. Kwon +8 more
TL;DR: A hyaluronic acid-rich node and duct system (HAR-NDS) was found on the surface of internal organs of mice, and inside their blood and lymph vessels as mentioned in this paper.