E
Emilie Montellier
Researcher at University of California, Irvine
Publications - 21
Citations - 3229
Emilie Montellier is an academic researcher from University of California, Irvine. The author has contributed to research in topics: Histone code & Histone H2A. The author has an hindex of 14, co-authored 19 publications receiving 2709 citations. Previous affiliations of Emilie Montellier include Joseph Fourier University & University of Grenoble.
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Journal ArticleDOI
Identification of 67 Histone Marks and Histone Lysine Crotonylation as a New Type of Histone Modification
Minjia Tan,Hao Luo,Sangkyu Lee,Fulai Jin,Jeong Soo Yang,Emilie Montellier,Thierry Buchou,Zhongyi Cheng,Sophie Rousseaux,Nisha Rajagopal,Zhike Lu,Zhen Ye,Qin Zhu,Joanna Wysocka,Yang Ye,Saadi Khochbin,Bing Ren,Yingming Zhao +17 more
TL;DR: The identification of 67 previously undescribed histone modifications is reported, increasing the current number of known histone marks by about 70%, and lysine crotonylation (Kcr) is investigated, confirming that it represents an evolutionarily-conserved histone posttranslational modification.
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Lysine 2-hydroxyisobutyrylation is a widely distributed active histone mark
Lunzhi Dai,Chao Peng,Emilie Montellier,Zhike Lu,Yue Chen,Haruhiko Ishii,Alexandra Debernardi,Thierry Buchou,Sophie Rousseaux,Fulai Jin,Benjamin R. Sabari,Zhiyou Deng,C. David Allis,Bing Ren,Saadi Khochbin,Yingming Zhao +15 more
TL;DR: It is shown that in male germ cells, H4K8hib is associated with active gene transcription in meiotic and post-meiotic cells and its critical role on the regulation of chromatin functions is suggested.
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Bromodomain‐dependent stage‐specific male genome programming by Brdt
Jonathan Gaucher,Fayçal Boussouar,Emilie Montellier,Sandrine Curtet,Thierry Buchou,Sarah Bertrand,Patrick Héry,Sylvie Jounier,Arnaud Depaux,Anne-Laure Vitte,Philippe Guardiola,Karin Pernet,Alexandra Debernardi,Fabrice Lopez,Hélène Holota,Jean Imbert,Debra J. Wolgemuth,Matthieu Gérard,Sophie Rousseaux,Saadi Khochbin +19 more
TL;DR: Bdt is a unique and essential regulator of male germ cell differentiation, which, by using various domains in a developmentally controlled manner, first drives a specific spermatogenic gene expression program, and later controls the tight packaging of the male genome.
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Chromatin-to-nucleoprotamine transition is controlled by the histone H2B variant TH2B
Emilie Montellier,Fayçal Boussouar,Sophie Rousseaux,Kai Zhang,Thierry Buchou,François Fenaille,Hitoshi Shiota,Alexandra Debernardi,Patrick Héry,Sandrine Curtet,Mahya Jamshidikia,Sophie Barral,Hélène Holota,Aurélie Bergon,Fabrice Lopez,Philippe Guardiola,Karin Pernet,Jean Imbert,Carlo Petosa,Minjia Tan,Minjia Tan,Yingming Zhao,Yingming Zhao,Matthieu Gérard,Saadi Khochbin +24 more
TL;DR: TH2B is a unique histone variant that plays a key role in the histone-to-protamine packing of the male genome and guides genome-wide chromatin transitions that both precede and follow transmission of themale genome to the egg.
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Dynamic Competing Histone H4 K5K8 Acetylation and Butyrylation Are Hallmarks of Highly Active Gene Promoters
Afsaneh Goudarzi,Di Zhang,He Huang,Sophie Barral,Oh Kwang Kwon,Shankang Qi,Zhanyun Tang,Thierry Buchou,Anne-Laure Vitte,Tieming He,Zhongyi Cheng,Emilie Montellier,Jonathan Gaucher,Sandrine Curtet,Alexandra Debernardi,Guillaume Charbonnier,Denis Puthier,Carlo Petosa,Daniel Panne,Sophie Rousseaux,Robert G. Roeder,Yingming Zhao,Saadi Khochbin +22 more
TL;DR: This work investigates the butyrylation of histone H4 lysine 5 and 8 at gene promoters where acetylation guides the binding of Brdt, a bromodomain-containing protein, thereby mediating stage-specific gene expression programs and post-meiotic chromatin reorganization.