E
Erica Wynne-Jones
Researcher at University of Melbourne
Publications - 5
Citations - 1136
Erica Wynne-Jones is an academic researcher from University of Melbourne. The author has contributed to research in topics: Downregulation and upregulation & CD8. The author has an hindex of 3, co-authored 5 publications receiving 843 citations.
Papers
More filters
Journal ArticleDOI
Hobit and Blimp1 instruct a universal transcriptional program of tissue residency in lymphocytes.
Laura K. Mackay,Laura K. Mackay,Martina Minnich,Natasja A. M. Kragten,Yang Liao,Yang Liao,Benjamin Nota,Cyril Seillet,Cyril Seillet,Ali Zaid,Kevin Man,Kevin Man,Simon Preston,Simon Preston,David Freestone,Asolina Braun,Erica Wynne-Jones,Felix M. Behr,Regina Stark,Daniel G. Pellicci,Daniel G. Pellicci,Dale I. Godfrey,Dale I. Godfrey,Gabrielle T. Belz,Gabrielle T. Belz,Marc Pellegrini,Marc Pellegrini,Thomas Gebhardt,Meinrad Busslinger,Wei Shi,Wei Shi,Francis R. Carbone,René A. W. van Lier,Axel Kallies,Axel Kallies,Klaas P. J. M. van Gisbergen +35 more
TL;DR: In this paper, the authors identify Hobit and Blimp1 as central regulators of a universal program that instructs tissue retention in diverse tissue-resident lymphocyte populations, including NKT cells and liver-resident NK cells.
Journal ArticleDOI
T-box Transcription Factors Combine with the Cytokines TGF-β and IL-15 to Control Tissue-Resident Memory T Cell Fate
Laura K. Mackay,Erica Wynne-Jones,David Freestone,Daniel G. Pellicci,Daniel G. Pellicci,Lisa A. Mielke,Dane M. Newman,Asolina Braun,Frederick Masson,Frederick Masson,Axel Kallies,Gabrielle T. Belz,Francis R. Carbone +12 more
TL;DR: It is demonstrated that the T-box transcription factors Eomes and T-bet combined to control CD8(+)CD103(+) Trm cell formation, such that their coordinate downregulation was crucial for TGF-β cytokine signaling.
Journal ArticleDOI
Sphingosine 1-phosphate receptor 5 (S1PR5) regulates the peripheral retention of tissue-resident lymphocytes.
Maximilien Evrard,Erica Wynne-Jones,Changwei Peng,Yu Kato,Susan N Christo,Raissa Fonseca,Simone L Park,Thomas N. Burn,Maleika Osman,Sapna Devi,Jerold Chun,Scott N. Mueller,George Kannourakis,Stuart P. Berzins,Stuart P. Berzins,Daniel G. Pellicci,William R. Heath,Stephen C. Jameson,Laura K. Mackay +18 more
TL;DR: In this paper, the authors identify the T-bet-ZEB2-S1PR5 axis as a previously unappreciated mechanism modulating the generation of tissue-resident lymphocytes.
Journal ArticleDOI
Metabolic characteristics of CD8 + T cell subsets in young and aged individuals are not predictive of functionality
Kylie M. Quinn,Kylie M. Quinn,Tabinda Hussain,Felix Kraus,Luke E. Formosa,Wai K Lam,Michael J Dagley,Eleanor C Saunders,Lisa M Assmus,Lisa M Assmus,Erica Wynne-Jones,Liyen Loh,Carolien E. van de Sandt,Carolien E. van de Sandt,Lucy Cooper,Kim L. Good-Jacobson,Katherine Kedzierska,Laura K. Mackay,Malcolm J. McConville,Georg Ramm,Georg Ramm,Michael T. Ryan,Nicole L. La Gruta +22 more
TL;DR: It is concluded that elevated SRC is a feature of TVM, but not TMEM, cells, is driven by physiological levels of IL-15, and is not indicative of enhanced functionality in CD8+ T cells.
Journal ArticleDOI
Publisher Correction: Metabolic characteristics of CD8+ T cell subsets in young and aged individuals are not predictive of functionality.
Kylie M. Quinn,Kylie M. Quinn,Tabinda Hussain,Felix Kraus,Luke E. Formosa,Wai K Lam,Michael J Dagley,Eleanor C Saunders,Lisa M Assmus,Lisa M Assmus,Erica Wynne-Jones,Liyen Loh,Carolien E. van de Sandt,Carolien E. van de Sandt,Lucy Cooper,Kim L. Good-Jacobson,Katherine Kedzierska,Laura K. Mackay,Malcolm J. McConville,Georg Ramm,Georg Ramm,Michael T. Ryan,Nicole L. La Gruta +22 more
TL;DR: An amendment to this paper has been published and can be accessed via a link at the top of the paper.