E
Eugene Braunwald
Researcher at Brigham and Women's Hospital
Publications - 1758
Citations - 278949
Eugene Braunwald is an academic researcher from Brigham and Women's Hospital. The author has contributed to research in topics: Myocardial infarction & TIMI. The author has an hindex of 230, co-authored 1711 publications receiving 264576 citations. Previous affiliations of Eugene Braunwald include Boston University & University of California, San Francisco.
Papers
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Journal ArticleDOI
Edoxaban versus Warfarin in Patients with Atrial Fibrillation at the Extremes of Body Weight: An Analysis from the ENGAGE AF-TIMI 48 Trial.
Giuseppe Boriani,Christian T. Ruff,Julia F Kuder,Minggao Shi,Hans Lanz,Elliott M. Antman,Eugene Braunwald,Robert P. Giugliano +7 more
TL;DR: Patients with LBW in ENGAGE AF-TIMI 48 had in general a more fragile clinical status and poorer international normalized ratio control, resulting in similar efficacy compared with warfarin, while major or clinically relevant non-MB and net outcomes were most favorable with edoxaban as compared to warFarin in LBW patients.
Journal ArticleDOI
Eugene Braunwald, MD and the early years of hypertrophic cardiomyopathy: a conversation with Dr. Barry J. Maron.
Barry J. Maron,Eugene Braunwald +1 more
TL;DR: It is appropriate at this time to reflect on how and why this important disease was transformed from the subject of a few anecdotal case reports into a robust and treatable clinical entity ultimately regarded as a common genetic heart disease and the most frequent cause of sudden death in young individuals.
Journal ArticleDOI
Effect of enoxaparin versus unfractionated heparin in diabetic patients with ST-elevation myocardial infarction in the Enoxaparin and Thrombolysis Reperfusion for Acute Myocardial Infarction Treatment-Thrombolysis In Myocardial Infarction study 25 (ExTRACT-TIMI 25) trial.
David A. Morrow,Elliott M. Antman,Sabina A. Murphy,Jie Qin,Mikhail Ruda,Sema Güneri,Ashok Jacob,Andrzej Budaj,Eugene Braunwald +8 more
TL;DR: In a subgroup analysis, a reperfusion strategy including enoxaparin significantly improved outcomes compared with UFH among high-risk STEMI patients with DM undergoing fibrinolysis.
Book ChapterDOI
Myocardial Stunning and Hibernation: Mechanisms and Clinical Implication
TL;DR: The concept of myocardial stunning and hibernation is reviewed and potential mechanism for stunned myocardium include alterations in calcium homeostasis and oxygen free radical damage.
Journal ArticleDOI
Association between angiographic complications and clinical outcomes among patients with acute coronary syndrome undergoing percutaneous coronary intervention: an EARLY ACS (Early Glycoprotein IIb/IIIa Inhibition in Non-ST-Segment Elevation Acute Coronary Syndrome) angiographic substudy.
Yuri B. Pride,Satishkumar Mohanavelu,Cafer Zorkun,Vijayalakshmi Kunadian,Robert P. Giugliano,L. Kristin Newby,Eugene Braunwald,Robert M. Califf,Robert A. Harrington,C. Michael Gibson,Early Acs Investigators +10 more
TL;DR: Among high-risk NSTEACS patients undergoing an invasive strategy, the incidence of intraprocedural complications is high, and the occurrence of these complications is associated with worse clinical outcomes independent of epicardial and myocardial perfusion.