Eva Harris

TL;DR: DENV-3, subtype III isolates from mild and severe disease outbreaks formed genetically distinct groups, which suggests a role for viral genetics in DHF.

TL;DR: It is suggested that ZIKV spreads from basal and parietal decidua to chorionic villi and amniochorionic membranes and that targeting TIM1 could suppress infection at the uterine-placental interface.

TL;DR: It is shown that passive administration of anti-DV antibodies is sufficient to enhance DV infection and disease in mice using both mouse-adapted and clinical DV isolates, and a genetically engineered antibody variant that cannot bind FcγR exhibited prophylactic and therapeutic efficacy against ADE-induced lethal challenge.

TL;DR: As dengue disease spreads to different parts of the globe several investigators have reported difficulties in using the system and some have had to create new categories or new case definitions to represent the observed patterns of disease more accurately.

TL;DR: Dengue virus (DENV) is a member of the Flavivirus genus of the Flavoriviridae family of enveloped, positive-strand RNA viruses.