Eva Harris

TL;DR: In a hospital and health center-based study in Nicaragua, fluid intake during the 24 hours before being seen by a clinician was statistically associated with decreased risk for hospitalization of dengue fever patients.

TL;DR: ZIKV infection in early pregnancy could target proliferating cell column cytotrophoblasts and Hofbauer cells, amplifying infection in basal decidua and chorionic villi and enabling transplacental transmission.

TL;DR: An international laboratory-response consortium for flaviviruses with a decentralized biobank of well-characterized samples to facilitate assay validation is suggested, and access to proficiency panels are needed to ensure quality control, in additional to in-country capacity building.

TL;DR: It is shown that long-lived CD14+ cells generated from CD34+ hematopoietic progenitors carry DC-SIGN and differentiate into immature DC in the presence of granulocyte-macrophage colony-stimulating factor, and the results suggest that interstitial CD14+.

TL;DR: This work elucidates the first in-depth characterization of human CD8+ T cells responding to ZIKV infection, characterized by a polyfunctional IFN-γ signature with upregulation of TNF-α, TNF receptors, and related activation markers, such as CD69, as well as a cytotoxic signature characterized by strong up regulation of GZMB and CRTAM.