Eva Harris

TL;DR: It is demonstrated that alpha/beta interferon (IFN-α/β) and IFN-γ receptors have critical, nonoverlapping functions in resolving primary DEN infection in mice and the IFN system plays a more important role than T- and B-cell-dependent immunity in resistance to primary DEN infections in mice.

TL;DR: Interestingly, secondary infection was not significantly correlated with DHF/DSS, in contrast to previous studies in Southeast Asia, as evidenced by the analysis of this epidemic.

TL;DR: A cross-sectional study conducted on 984 and 313 hospitalized children with confirmed DENV infections during two time periods, respectively, in the same hospitals in Nicaragua provides new data to characterize the pathogenic potential of distinct DENV serotypes in human populations.

TL;DR: Depending on the cell type and viral isolate, blocks that limit the production of infectious virus in vitro may occur at distinct steps in the pathway of cellular infection, as observed with the antibody-dependent pathway of infection.

TL;DR: Zika virus, chikungunya virus, and dengue virus result in similar clinical presentations, and coinfections may be relatively common.