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Ewa Stępień

Researcher at Jagiellonian University

Publications -  161
Citations -  3537

Ewa Stępień is an academic researcher from Jagiellonian University. The author has contributed to research in topics: Platelet activation & Medicine. The author has an hindex of 28, co-authored 131 publications receiving 2734 citations. Previous affiliations of Ewa Stępień include Jagiellonian University Medical College.

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EVpedia: a community web portal for extracellular vesicles research

Dae-Kyum Kim, +97 more
- 15 Mar 2015 - 
TL;DR: An improved version of EVpedia, a public database for EVs research, is presented, which contains a database of publications and vesicular components, identification of orthologous vesicle components, bioinformatic tools and a personalized function.
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Reduced clot permeability and susceptibility to lysis in patients with acute coronary syndrome: effects of inflammation and oxidative stress.

TL;DR: This first study of clot properties in patients during an ACS demonstrated that compared with stable angina patients, their clots are composed of dense networks that are more resistant to lysis and these features are correlated with raised CRP and oxidative stress.
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Hyperglycemia is associated with enhanced thrombin formation, platelet activation, and fibrin clot resistance to lysis in patients with acute coronary syndrome.

TL;DR: Hyperglycemia in acute coronary syndrome is associated with enhanced local thrombin generation and platelet activation, as well as unfavorably altered clot features in patients with and without a previous history of diabetes.
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Role of microRNAs in endothelial cell pathophysiology.

TL;DR: Review of the current knowledge about the role of miRNAs in endothelial cells with emphasis on the regulation of cellular senescence, angiogenesis, and vascular inflammation concludes that additional research is needed before miRNA expression analysis can be used in routine clinical setting.
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Altered Fibrin Clot Structure/Function in Patients With Cryptogenic Ischemic Stroke

TL;DR: Clots from stroke patients with PFO were more permeable and showed shorter lysis time compared to those without PFO, and this was related to lower proportion of smokers in the former group.