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Felix Mölder
Researcher at University of Duisburg-Essen
Publications - 10
Citations - 1280
Felix Mölder is an academic researcher from University of Duisburg-Essen. The author has contributed to research in topics: Cellular immunity & Chemokine receptor. The author has an hindex of 5, co-authored 9 publications receiving 428 citations.
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Journal ArticleDOI
Eleven grand challenges in single-cell data science
David Lähnemann,David Lähnemann,Johannes Köster,Johannes Köster,Ewa Szczurek,Davis J. McCarthy,Davis J. McCarthy,Stephanie C. Hicks,Mark D. Robinson,Catalina A. Vallejos,Catalina A. Vallejos,Kieran R Campbell,Kieran R Campbell,Niko Beerenwinkel,Niko Beerenwinkel,Ahmed Mahfouz,Ahmed Mahfouz,Luca Pinello,Luca Pinello,Pavel Skums,Alexandros Stamatakis,Alexandros Stamatakis,Camille Stephan Otto Attolini,Samuel Aparicio,Samuel Aparicio,Jasmijn A. Baaijens,Marleen Balvert,Marleen Balvert,Buys de Barbanson,Antonio Cappuccio,Giacomo Corleone,Bas E. Dutilh,Bas E. Dutilh,Maria Florescu,Victor Guryev,Rens Holmer,Katharina Jahn,Katharina Jahn,Thamar Jessurun Lobo,Emma M. Keizer,Indu Khatri,Szymon M. Kielbasa,Jan O. Korbel,Alexey M. Kozlov,Tzu Hao Kuo,Boudewijn P. F. Lelieveldt,Boudewijn P. F. Lelieveldt,Ion I. Mandoiu,John C. Marioni,John C. Marioni,John C. Marioni,Tobias Marschall,Tobias Marschall,Felix Mölder,Amir Niknejad,Lukasz Raczkowski,Marcel J. T. Reinders,Marcel J. T. Reinders,Jeroen de Ridder,Antoine-Emmanuel Saliba,Antonios Somarakis,Oliver Stegle,Oliver Stegle,Fabian J. Theis,Huan Yang,Alexander Zelikovsky,Alexander Zelikovsky,Alice C. McHardy,Benjamin J. Raphael,Sohrab P. Shah,Alexander Schönhuth,Alexander Schönhuth +71 more
TL;DR: This compendium is for established researchers, newcomers, and students alike, highlighting interesting and rewarding problems for the coming years in single-cell data science.
Journal ArticleDOI
Sustainable data analysis with Snakemake.
Felix Mölder,Kim Philipp Jablonski,Kim Philipp Jablonski,Brice Letcher,Michael B Hall,Christopher Tomkins-Tinch,Christopher Tomkins-Tinch,Vanessa Sochat,Jan Forster,Jan Forster,Soohyun Lee,Sven Twardziok,Alexander Kanitz,Alexander Kanitz,Andreas Wilm,Manuel Holtgrewe,Sven Rahmann,Sven Nahnsen,Johannes Köster,Johannes Köster +19 more
TL;DR: It is shown how the popular workflow management system Snakemake can be used to guarantee reproducibility, and how it enables an ergonomic, combined, unified representation of all steps involved in data analysis, ranging from raw data processing, to quality control and fine-grained, interactive exploration and plotting of final results.
Journal ArticleDOI
The Role of Pre-existing Cross-Reactive Central Memory CD4 T-Cells in Vaccination With Previously Unseen Influenza Strains
Mikalai Nienen,Ulrik Stervbo,Felix Mölder,Sviatlana Kaliszczyk,Leon Kuchenbecker,Ludmila Gayova,Brunhilde Schweiger,Karsten Jürchott,Jochen Hecht,Avidan U. Neumann,Sven Rahmann,Timm H. Westhoff,Petra Reinke,Andreas Thiel,Nina Babel,Nina Babel +15 more
TL;DR: Analysis of cellular and humoral immunity in healthy individuals before and after vaccination with seasonal influenza vaccine suggests that the deliberate recruitment of pre-existing cross-reactive cellular memory might help to improve vaccination outcome.
Journal ArticleDOI
SLAMF7 and IL-6R define distinct cytotoxic versus helper memory CD8+ T cells
Lucie Loyal,Sarah Warth,Karsten Jürchott,Felix Mölder,Christos Nikolaou,Nina Babel,Mikalai Nienen,Sibel Durlanik,Regina Stark,Beate Kruse,Marco Frentsch,Robert Sabat,Kerstin Wolk,Andreas Thiel +13 more
TL;DR: It is demonstrated that analogous CD8+ memory T-cell subsets exist, characterized by identical chemokine receptor expression signatures and controlled by similar generic programs.
Peer Review
Sustainable data analysis with Snakemake [version 1; peer review: 1 approved, 1 approved with reservations]
Felix Mölder,Kim Philipp Jablonski,Brice Letcher,Michael B Hall,Christopher Tomkins-Tinch,Vanessa Sochat,Jan Forster,Soohyun Lee,Sven Twardziok,Alexander Kanitz,Andreas Wilm,Manuel Holtgrewe,Sven Rahmann,Sven Nahnsen,Johannes Köster +14 more
TL;DR: It is postulate that it is equally important to ensure adaptability and transparency, the ability to modify the analysis to answer extended or slightly different research questions, as well as to ensure Open Peer Review.