K
Katharina Jahn
Researcher at ETH Zurich
Publications - 39
Citations - 2642
Katharina Jahn is an academic researcher from ETH Zurich. The author has contributed to research in topics: Genome & Gene cluster. The author has an hindex of 17, co-authored 35 publications receiving 1662 citations. Previous affiliations of Katharina Jahn include Ludwig Maximilian University of Munich & Bielefeld University.
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Journal ArticleDOI
Eleven grand challenges in single-cell data science
David Lähnemann,David Lähnemann,Johannes Köster,Johannes Köster,Ewa Szczurek,Davis J. McCarthy,Davis J. McCarthy,Stephanie C. Hicks,Mark D. Robinson,Catalina A. Vallejos,Catalina A. Vallejos,Kieran R Campbell,Kieran R Campbell,Niko Beerenwinkel,Niko Beerenwinkel,Ahmed Mahfouz,Ahmed Mahfouz,Luca Pinello,Luca Pinello,Pavel Skums,Alexandros Stamatakis,Alexandros Stamatakis,Camille Stephan Otto Attolini,Samuel Aparicio,Samuel Aparicio,Jasmijn A. Baaijens,Marleen Balvert,Marleen Balvert,Buys de Barbanson,Antonio Cappuccio,Giacomo Corleone,Bas E. Dutilh,Bas E. Dutilh,Maria Florescu,Victor Guryev,Rens Holmer,Katharina Jahn,Katharina Jahn,Thamar Jessurun Lobo,Emma M. Keizer,Indu Khatri,Szymon M. Kielbasa,Jan O. Korbel,Alexey M. Kozlov,Tzu Hao Kuo,Boudewijn P. F. Lelieveldt,Boudewijn P. F. Lelieveldt,Ion I. Mandoiu,John C. Marioni,John C. Marioni,John C. Marioni,Tobias Marschall,Tobias Marschall,Felix Mölder,Amir Niknejad,Lukasz Raczkowski,Marcel J. T. Reinders,Marcel J. T. Reinders,Jeroen de Ridder,Antoine-Emmanuel Saliba,Antonios Somarakis,Oliver Stegle,Oliver Stegle,Fabian J. Theis,Huan Yang,Alexander Zelikovsky,Alexander Zelikovsky,Alice C. McHardy,Benjamin J. Raphael,Sohrab P. Shah,Alexander Schönhuth,Alexander Schönhuth +71 more
TL;DR: This compendium is for established researchers, newcomers, and students alike, highlighting interesting and rewarding problems for the coming years in single-cell data science.
Journal ArticleDOI
The coffee genome provides insight into the convergent evolution of caffeine biosynthesis
Lorenzo Carretero-Paulet,Alexis Dereeper,Gaëtan Droc,Romain Guyot,Marco Pietrella,Chunfang Zheng,Adriana Alberti,François Anthony,G. Aprea,Jean-Marc Aury,Pascal Bento,Maria Bernard,Stéphanie Bocs,Claudine Campa,Alberto Cenci,Alberto Cenci,Marie Christine Combes,Dominique Crouzillat,Corinne Da Silva,Loretta Daddiego,Fabien De Bellis,Stéphane Dussert,Olivier Garsmeur,Thomas Gayraud,Valentin Guignon,Katharina Jahn,Katharina Jahn,Véronique Jamilloux,Thierry Joët,Karine Labadie,Tianying Lan,Tianying Lan,Julie Leclercq,Maud Lepelley,Thierry Leroy,Leiting Li,Pablo Librado,Loredana Lopez,Adriana Muñoz,Adriana Muñoz,Benjamin Noel,Alberto Pallavicini,Gaetano Perrotta,Valérie Poncet,David Pot,Priyono,Michel Rigoreau,Mathieu Rouard,Julio Rozas,Christine Tranchant-Dubreuil,Robert VanBuren,Qiong Zhang,Alan Carvalho Andrade,Xavier Argout,Benoît Bertrand,Alexandre de Kochko,Giorgio Graziosi,Giorgio Graziosi,Robert J Henry,Jayarama,Ray Ming,Chifumi Nagai,Steve Rounsley,David Sankoff,Giovanni Giuliano,Victor A. Albert,Patrick Wincker,Patrick Wincker,Patrick Wincker,Philippe Lashermes +69 more
TL;DR: The Coffea canephora (coffee) genome was sequenced and identified a conserved gene order, and comparative analyses of caffeine NMTs demonstrate that these genes expanded through sequential tandem duplications independently of genes from cacao and tea, suggesting that caffeine in eudicots is of polyphyletic origin.
Journal ArticleDOI
Tree inference for single-cell data
TL;DR: In this paper, a stochastic search algorithm is proposed to identify the evolutionary history of a tumor from noisy and incomplete mutation profiles of single cells using a Markov chain Monte Carlo sampling scheme.
Journal ArticleDOI
Clonal evolution of acute myeloid leukemia revealed by high-throughput single-cell genomics.
Kiyomi Morita,Kiyomi Morita,Feng Wang,Katharina Jahn,Katharina Jahn,Tianyuan Hu,Tomoyuki Tanaka,Yuya Sasaki,Jack Kuipers,Jack Kuipers,Sanam Loghavi,Sa A. Wang,Yuanqing Yan,Ken Furudate,Ken Furudate,Jairo Matthews,Latasha Little,Curtis Gumbs,Jianhua Zhang,Xingzhi Song,Erika Thompson,Keyur P. Patel,Carlos E. Bueso-Ramos,Courtney D. DiNardo,Farhad Ravandi,Elias Jabbour,Michael Andreeff,Jorge E. Cortes,Kapil N. Bhalla,Guillermo Garcia-Manero,Hagop M. Kantarjian,Marina Konopleva,Daisuke Nakada,Nicholas Navin,Niko Beerenwinkel,Niko Beerenwinkel,P. Andrew Futreal,Koichi Takahashi +37 more
TL;DR: Using a single-cell DNA sequencing, the clonal architecture and mutational histories of 123 acute myeloid leukemia (AML) patients are reported, revealing cell-level mutation co-occurrence and enables reconstruction ofmutational histories characterized by linear and branching patterns of clonal evolution.
Journal ArticleDOI
Microbe-host interplay in atopic dermatitis and psoriasis
Nanna Fyhrquist,Nanna Fyhrquist,Gareth Muirhead,Stefanie Prast-Nielsen,Marine Jeanmougin,Péter Oláh,Tiina Skoog,Gerome Jules-Clement,Micha Feld,Mauricio Barrientos-Somarribas,Hanna Sinkko,Hanna Sinkko,Ellen H. van den Bogaard,Patrick L.J.M. Zeeuwen,Gijs Rikken,Joost Schalkwijk,Hanna Niehues,Walter Däubener,Silvia Kathrin Eller,Helen Alexander,Davide Pennino,Sari Suomela,Ioannis Tessas,Emilia Lybeck,Anna M. Baran,Hamid Darban,Roopesh Singh Gangwar,Ulrich Gerstel,Katharina Jahn,Piia Karisola,Lee Yan,Britta Hansmann,Shintaro Katayama,Stephan Meller,Max Bylesjö,Philippe Hupé,Francesca Levi-Schaffer,Dario Greco,Dario Greco,Annamari Ranki,Jens M. Schröder,Jonathan Barker,Juha Kere,Juha Kere,Sophia Tsoka,Antti Lauerma,Vassili Soumelis,Vassili Soumelis,Frank O. Nestle,Bernhard Homey,Björn Andersson,Harri Alenius,Harri Alenius +52 more
TL;DR: By analyses of skin microbiome and host transcriptome of AD and PSO patients, the authors find distinct microbial and disease-related gene transcriptomic signatures that differentiate both diseases.