F
Florence Demenais
Researcher at French Institute of Health and Medical Research
Publications - 228
Citations - 14269
Florence Demenais is an academic researcher from French Institute of Health and Medical Research. The author has contributed to research in topics: Genome-wide association study & Population. The author has an hindex of 58, co-authored 225 publications receiving 13069 citations. Previous affiliations of Florence Demenais include Institut Gustave Roussy & Foundation Center.
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Journal ArticleDOI
Genome-Wide Association Study of Fluorescent Oxidation Products Accounting for Tobacco Smoking Status in Adults from the French EGEA Study
Laurent Orsi,Patricia Margaritte-Jeannin,Miora Andrianjafimasy,Orianne Dumas,Hamida Mohamdi,Emmanuelle Bouzigon,Florence Demenais,Régis Matran,Farid Zerimech,Rachel Nadif,Marie-Hélène Dizier +10 more
TL;DR: This study, which is the first genome-wide association study of FlOPs, provides new insights into the pathophysiology of chronic OS-related diseases.
Journal Article
Descriptive analysis of breast cancer in African-American women at Howard University Hospital, 1960-1987
R. Williams,A. E. Laing,Florence Demenais,G. Kissling,Barry L. Gause,V. W. Chen,George E. Bonney +6 more
TL;DR: Pre- and postmenopausal women are compared, revealing differences in reproductive experience that may contribute to the increasing incidence of breast cancer seen among younger women in recent years.
Journal ArticleDOI
Regressive threshold model for familial analysis of complex diseases with variable age of onset
TL;DR: The regressive threshold model (RTM) is extended to account for a variable age of onset of complex diseases and may prove helpful in contributing to identification of genes underlying complex diseases, since it can easily include linked marker loci and linkage disequilibrium.
Journal ArticleDOI
Studies on an isolated West Indies population: IV. Genetic study of hearing loss.
TL;DR: Segregation analysis of hearing loss was performed and revealed that familial aggregation could be entirely explained by a single recessive gene with high frequency (0.40).
Genome-wide association study identifies a new melanoma susceptibility locus at 1q21.3
Stuart MacGregor,Grant W. Montgomery,Jimmy Z. Liu,Zhen Zhen Zhao,Anjali K. Henders,Mitchell S. Stark,Helen Schmid,Elizabeth A. Holland,David L. Duffy,Mingfeng Zhang,Jodie N. Painter,Dale R. Nyholt,Judith A. Maskiell,Jodie Jetann,Michele Ferguson,Anne E. Cust,Jenkins,David C. Whiteman,Håkan Olsson,Susana Puig,Giovanna Bianchi-Scarrà,Johan Hansson,Florence Demenais,Maria Teresa Landi,Tadeusz Dębniak,R.M. Mackie,Esther Azizi,Brigitte Bressac-de Paillerets,Alisa M. Goldstein,Peter A. Kanetsky,Nelleke A. Gruis,David E. Elder,Julia Newton-Bishop,D T Bishop,Mark M. Iles,Per Helsing,Christopher I. Amos,Qingyi Wei,Li-E Wang,Jeffrey E. Lee,Abrar A. Qureshi,Richard F. Kefford,G.G. Giles,Bruce K. Armstrong,Joanne F. Aitken,Jiali Han,John L. Hopper,J.M. Trent,Kevin M. Brown,Nicholas G. Martin,Graham J. Mann,Nicholas K. Hayward +51 more
TL;DR: A genome-wide association study of melanoma in a discovery cohort of 2,168 Australian individuals with melanoma and 4,387 control individuals confirms several previously characterized melanoma-associated loci at MC1R, ASIP and MTAP–CDKN2A and shows evidence suggesting that melanoma associates with 1q42.12.