F
Florence Demenais
Researcher at French Institute of Health and Medical Research
Publications - 228
Citations - 14269
Florence Demenais is an academic researcher from French Institute of Health and Medical Research. The author has contributed to research in topics: Genome-wide association study & Population. The author has an hindex of 58, co-authored 225 publications receiving 13069 citations. Previous affiliations of Florence Demenais include Institut Gustave Roussy & Foundation Center.
Papers
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Journal ArticleDOI
Identification of OCA2 as a novel locus for the co-morbidity of asthma-plus-eczema
Patricia Margaritte-Jeannin,Ashley Budu-Aggrey,Markus J. Ege,Anne-Marie Madore,Christophe Linhard,Hamida Mohamdi,Erika von Mutius,Raquel Granell,Florence Demenais,Catherine Laprise,Emmanuelle Bouzigon,Marie-Hélène Dizier +11 more
TL;DR: In this paper, a meta-analysis of four GWAS (genome-Wide Association Study) of the combined asthma-plus-eczema phenotype (total of 8,807 European-ancestry subjects of whom 1,208 subjects had both asthma and eczema) was conducted.
Journal ArticleDOI
PID1 is associated to a respiratory endotype related to occupational exposures to irritants.
Miora Valérie Andrianjafimasy,Laurent Orsi,Patricia Margaritte-Jeannin,Hamida Mohamdi,Florence Demenais,Nicole Le Moual,Régis Matran,Régis Matran,Farid Zerimech,Farid Zerimech,Orianne Dumas,Marie-Hélène Dizier,Rachel Nadif +12 more
TL;DR: In this paper, the association between the asthma endotype and genetic variants (4715 SNPs) located in 422 genes involved in the response to oxidative stress in adults from the Epidemiological study on the Genetic and Environment of Asthma.
Journal Article
HLA and leprosy
Florence Demenais,N. Feingold +1 more
TL;DR: Although there is now accumulating evidence that the host response to Mycobacterium leprae is genetically controlled, the nature of the genetic component is still imprecise and a better understanding of the underlying genetic mechanisms is needed.
Proceedings ArticleDOI
Influence of gene-by-sex interaction on time-to-asthma onset: a large-scale genome-wide meta-analysis
Raphael Veil,Hamida Mohamdi,Raquel Granell,Markus J. Ege,Maxim B. Freidin,Medea Imboden,Alan James,Deborah Jarvis,Elza Khusnutdinova,Catherine Laprise,Patricia Margaritte-Jeannin,Ludmila O. Ogorodova,Chloé Sarnowski,null Marie-Helene,Dizier A. John Henderson,A. S. Karunas,Erika von Mutius,Nicole Probst-Hensch,Bénédicte Leynaert,Florence Demenais,Emmanuelle Bouzigon +20 more
TL;DR: This paper presents a meta-analysis of 120 cases of central giant cell granuloma located in Switzerland over a 12-year period and shows clear patterns of prognosis for meningitis and organ prolapse in women.
Journal Article
Endocrine polyadenomatosis of 2a type (MEN 2a). Clinical and genetic study of a family
P J Guillausseau,C Guillausseau,C Calmettes,N. Feingold,Florence Demenais,Hagay Sobol,J Gony,Jacques Hors,G. Schaison,D Seret +9 more
TL;DR: In a large kindred with multiple endocrine neoplasia type 2a (MEN 2a) (137 members, 5 generations), bilateral thyroid medullary carcinoma was found in all affected members and results comfort the lack of linkage between MEN 2a and the HLA complex.