F
Florian Singer
Researcher at University of Bern
Publications - 156
Citations - 3846
Florian Singer is an academic researcher from University of Bern. The author has contributed to research in topics: Asthma & Spirometry. The author has an hindex of 28, co-authored 141 publications receiving 3128 citations. Previous affiliations of Florian Singer include University of Zurich & University Hospital of Bern.
Papers
More filters
Journal ArticleDOI
Consensus statement for inert gas washout measurement using multiple- and single- breath tests
Paul Robinson,Philipp Latzin,Sylvia Verbanck,Graham L. Hall,Alex Horsley,Monika Gappa,Cindy Thamrin,Hubertus G.M. Arets,Paul Aurora,Susanne I. Fuchs,Gregory G. King,Sooky Lum,Kenneth G. MacLeod,Manuel Paiva,J. Jane Pillow,Sarath Ranganathan,Felix Ratjen,Florian Singer,Samatha Sonnappa,Janet Stocks,Padmaja Subbarao,Bruce Thompson,P. Gustafsson +22 more
TL;DR: Recommendations are provided about these aspects, applicable to both the paediatric and adult testing environment, whilst outlining the important principles that are essential for the reader to understand.
Journal ArticleDOI
Clinical and inflammatory characteristics of the European U-BIOPRED adult severe asthma cohort
Dominick E. Shaw,Ana R. Sousa,Stephen J. Fowler,Louise Fleming,Graham Roberts,Graham Roberts,Julie Corfield,Julie Corfield,Ioannis Pandis,Aruna T. Bansal,Elisabeth H. Bel,Charles Auffray,Chris Compton,Hans Bisgaard,Enrica Bucchioni,Massimo Caruso,Pascal Chanez,Barbro Dahlén,Sven-Erik Dahlén,Kerry Dyson,Urs Frey,Thomas Geiser,Maria Gerhardsson de Verdier,David Gibeon,Yike Guo,Simone Hashimoto,Gunilla Hedlin,E. Jeyasingham,P.P. Hekking,Tim Higenbottam,Ildiko Horvath,Alan J. Knox,Norbert Krug,Veit J. Erpenbeck,L. Larsson,Nikos Lazarinis,John G. Matthews,Roelinde Middelveld,Paolo Montuschi,Jacek Musiał,David Myles,Laurie Pahus,Thomas Sandström,Wolfgang Seibold,Florian Singer,Karin Strandberg,Jørgen Vestbo,Nadja Hawwa Vissing,Christophe von Garnier,Ian M. Adcock,Scott Wagers,Anthony Rowe,Peter H. Howarth,Ariane H. Wagener,Ratko Djukanovic,Peter J. Sterk,Kian Fan Chung +56 more
TL;DR: U-BIOPRED is characterised by poor symptom control, increased comorbidity and airway inflammation, despite high levels of treatment, and is well suited to identify asthma phenotypes using the array of "omic" datasets that are at the core of this systems medicine approach.
Journal ArticleDOI
U-BIOPRED clinical adult asthma clusters linked to a subset of sputum omics
Diane Lefaudeux,Bertrand De Meulder,Matthew J. Loza,Nancy Peffer,Anthony Rowe,Frédéric Baribaud,Aruna T. Bansal,René Lutter,Ana R. Sousa,Julie Corfield,Ioannis Pandis,Per Bakke,Massimo Caruso,Pascal Chanez,Sven-Erik Dahlén,Louise Fleming,Stephen J. Fowler,Ildiko Horvath,Norbert Krug,Paolo Montuschi,Marek Sanak,Thomas Sandström,Dominic E. Shaw,Florian Singer,Peter J. Sterk,Graham Roberts,Ian M. Adcock,Ratko Djukanovic,Charles Auffray,Kian Fan Chung,Nora Adriaens,H. Ahmed,Antonios Aliprantis,Kjell Alving,Philipp Badorek,David Balgoma,Clair Barber,An Bautmans,Annelie F. Behndig,Elisabeth H. Bel,Jorge Beleta,Ann Berglind,Alix Berton,Jeanette Bigler,Hans Bisgaard,Grazyna Bochenek,Michael Boedigheimer,Klaus Bøonnelykke,Joost Brandsma,Armin Braun,Paul Brinkman,Dominic Burg,Davide Campagna,Leon Carayannopoulos,João P. Carvalho da Purfição Rocha,Amphun Chaiboonchoe,Romanas Chaleckis,Courtney Coleman,Chris Compton,Arnaldo D'Amico,Barbro Dahlén,Jorge De Alba,Pim de Boer,Inge De Lepeleire,Tamara Dekker,Ingrid Delin,Patrick Dennison,Annemiek Dijkhuis,Aleksandra Draper,J. M. Edwards,Rosalia Emma,Magnus Ericsson,Veit J. Erpenbeck,Damijan Erzen,Cornelia Faulenbach,Klaus Fichtner,Neil Fitch,Breda Flood,Urs Frey,Martina Gahlemann,Gabriella Galffy,Hector Gallart,Trevor Garret,Thomas Geiser,Jilaiha Gent,Maria Gerhardsson de Verdier,David Gibeon,Cristina Gómez,Kerry Gove,Neil Gozzard,Yike Guo,Simone Hashimoto,John Haughney,Gunilla Hedlin,Pieter-Paul Hekking,Elisabeth Henriksson,Lorraine Hewitt,Tim Higgenbottam,Uruj Hoda,Jans Hohlfeld,Cecile T.J. Holweg,Peter H. Howarth,Richard Hu,Sile Hu,Xugang Hu,Val Hudson,Anna James,Juliette Kamphuis,Erika Kennington,Dyson Kerry,Matthias Klüglich,Hugo H. Knobel,Richard G. Knowles,Alan J. Knox,Johan Kolmert,Jon R Konradsen,Maxim Kots,Linn Krueger,Scott Kuo,Maciej Kupczyk,Bart N. Lambrecht,Ann-Sofie Lantz,L. Larsson,Nikos Lazarinis,Saeeda Lone-Satif,Lisa Marouzet,Jane Martin,Sarah Masefield,Caroline Mathon,John G. Matthews,Alexander Mazein,Sally Meah,Andrea Maiser,Andrew Menzies-Gow,Leanne Metcalf,Roelinde Middelveld,Maria Mikus,Montse Miralpeix,Philips Monk,Nadia Mores,Clare S. Murray,Jacek Musiał,David Myles,Shama Naz,Katja Nething,Ben Nicholas,Ulf Nihlen,Peter Nilsson,Björn Nordlund,Jörgen Östling,Antonio Pacino,Laurie Pahus,Susanna Palkonnen,Stelios Pavlidis,Giorgio Pennazza,Anne Petrén,Sandy Pink,Anthony D. Postle,Pippa Powel,Malayka Rahman-Amin,Navin Rao,Lara Ravanetti,Emma Ray,Stacey N. Reinke,Leanne Reynolds,Kathrin Riemann,John H. Riley,Martine Robberechts,Amanda Roberts,Christos Rossios,Kirsty E. Russell,Michael Rutgers,Giuseppe Santini,Marco Sentoninco,Corinna Schoelch,James P.R. Schofield,Wolfgang Seibold,Ralf Sigmund,Marcus O.D. Sjödin,Paul Skipp,Barbara Smids,Caroline Smith,J.C. Smith,Katherine M. Smith,Päivi Söderman,Adesimbo Sogbesan,Doroteya Staykova,Karin Strandberg,Kai Sun,David Supple,Marton Szentkereszty,Lilla Tamasi,Kamran Tariq,John-Olof Thörngren,Bob Thornton,Jonathan Thorsen,Salvatore Valente,Wim van Aalderenm,Marianne A. van de Pol,Kees van Drunen,Marleen van Geest,Jenny Versnel,Jørgen Vestbo,Anton Vink,Nadja Hawwa Vissing,Christophe von Garnier,Arianne Wagerner,Scott Wagers,Frans Wald,Samantha Walker,Jonathan Ward,Zsoka Weiszhart,Kristiane Wetzel,Craig E. Wheelock,Coen Wiegman,Siân Williams,Susan J. Wilson,Ashley Woosdcock,Xian Yang,Elizabeth Yeyashingham,Wen Yu,Wilhelm Zetterquist,Koos Zwinderman +222 more
TL;DR: Clustering based on clinicophysiologic parameters yielded 4 stable and reproducible clusters of asthmatic patients that associate with different pathobiological pathways.
Journal ArticleDOI
The burden of severe asthma in childhood and adolescence: results from the paediatric U-BIOPRED cohorts.
Louise Fleming,Clare S. Murray,Aruna T. Bansal,Simone Hashimoto,Hans Bisgaard,Andrew Bush,Urs Frey,Gunilla Hedlin,Florian Singer,Wim M. C. van Aalderen,Nadja Hawwa Vissing,Zaraquiza Zolkipli,Zaraquiza Zolkipli,Anna Selby,Anna Selby,Stephen J. Fowler,Stephen J. Fowler,Dominick E. Shaw,Kian Fan Chung,Ana R. Sousa,Scott Wagers,Julie Corfield,Julie Corfield,Ioannis Pandis,Anthony Rowe,Elena Formaggio,Peter J. Sterk,Graham Roberts,Graham Roberts +28 more
TL;DR: In-depth phenotyping of children with severe preschool wheeze or severe asthma are usually atopic and have impaired quality of life that is associated with poor control and airflow limitation: a very different phenotype from adult severe asthma.
Journal ArticleDOI
A realistic validation study of a new nitrogen multiple-breath washout system
TL;DR: The lung model generates lung volumes under the conditions encountered during clinical MBW testing and enables realistic validation of MBW systems.