F
Frank Gross
Researcher at Dresden University of Technology
Publications - 12
Citations - 1156
Frank Gross is an academic researcher from Dresden University of Technology. The author has contributed to research in topics: Heterologous expression & Sorangium cellulosum. The author has an hindex of 10, co-authored 12 publications receiving 1103 citations. Previous affiliations of Frank Gross include Research Triangle Park & Saarland University.
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Journal ArticleDOI
Complete genome sequence of the myxobacterium Sorangium cellulosum
Susanne Schneiker,Olena Perlova,Olaf Kaiser,Klaus Gerth,Aysel Alici,Matthias Altmeyer,Daniela Bartels,Thomas Bekel,Stefan Beyer,Edna Bode,Helge B. Bode,Christoph J. Bolten,Jomuna V. Choudhuri,Sabrina D. Doss,Yasser A. Elnakady,Bettina Frank,Lars Gaigalat,Alexander Goesmann,Carolin Groeger,Frank Gross,Lars Jelsbak,Lotte Jelsbak,Jörn Kalinowski,Carsten Kegler,Tina Knauber,Sebastian Konietzny,Maren Kopp,Lutz Krause,Daniel Krug,Bukhard Linke,Taifo Mahmud,Rosa Martínez-Arias,Alice C. McHardy,Michelle Merai,Folker Meyer,Sascha Mormann,José Muñoz-Dorado,Juana Pérez,Silke Pradella,Shwan Rachid,Günter Raddatz,Frank Rosenau,Christian Rückert,Florenz Sasse,Maren Scharfe,Stephan C. Schuster,Garret Suen,Anke Treuner-Lange,Gregory J. Velicer,Frank-Jörg Vorhölter,Kira J. Weissman,Roy D. Welch,Silke C. Wenzel,David E. Whitworth,Susanne Wilhelm,Christoph Wittmann,Helmut Blöcker,Alfred Pühler,Rolf Müller +58 more
TL;DR: The complete genome sequence of the model Sorangium strain S. cellulosum So ce56 is reported, which produces several natural products and has morphological and physiological properties typical of the genus, and the circular genome is the largest bacterial genome sequenced to date.
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Heterologous Expression of a Myxobacterial Natural Products Assembly Line in Pseudomonads via Red/ET Recombineering
TL;DR: A straightforward strategy that combines the power of advanced DNA engineering in Escherichia coli with the utility of pseudomonads as the heterologous host for the analysis and mutagenesis of known and unknown secondary metabolite pathways is described.
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Efficient transfer of two large secondary metabolite pathway gene clusters into heterologous hosts by transposition.
Jun Fu,Silke C. Wenzel,Olena Perlova,Junping Wang,Frank Gross,Zhiru Tang,Yulong Yin,A. Francis Stewart,Rolf Müller,Youming Zhang +9 more
TL;DR: It is suggested that delivery by transposon will become the method of choice for delivery of large transgenes, particularly not only for metabolic engineering but also for general transgenesis in prokaryotes and eukaryotes.
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Bacterial type III polyketide synthases: phylogenetic analysis and potential for the production of novel secondary metabolites by heterologous expression in pseudomonads.
Frank Gross,Nora Luniak,Olena Perlova,Nikolaos Gaitatzis,Holger Jenke-Kodama,Klaus Gerth,Daniela Gottschalk,Elke Dittmann,Rolf Müller +8 more
TL;DR: The successful heterologous production of a secondary metabolite using a gene not expressed under administered laboratory conditions provides evidence for the usefulness of the approach to activate suchsecondary metabolite genes for the production of novel metabolites.
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Homo- und Hetero-Metall-Amide des Tris(tert-butylamino)methylsilans – Polycyclen und Cluster mit Li, Na, Mg, Al und Tl
TL;DR: In this article, the trisamide MeSi(tBuNAlMe2)3 (3) is obtained by complete substitution of the amino hydrogen atoms in tris(tert-butyl-amino)methylsilane.