F
Frederic Geissmann
Researcher at Memorial Sloan Kettering Cancer Center
Publications - 153
Citations - 43031
Frederic Geissmann is an academic researcher from Memorial Sloan Kettering Cancer Center. The author has contributed to research in topics: Monocyte & Macrophage. The author has an hindex of 73, co-authored 147 publications receiving 37781 citations. Previous affiliations of Frederic Geissmann include New York University & University of Paris.
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Journal ArticleDOI
Retinoids Regulate Survival and Antigen Presentation by Immature Dendritic Cells
Frederic Geissmann,Patrick Revy,Nicole Brousse,Yves Lepelletier,Claudia Folli,Anne Durandy,Pierre Chambon,Michel Dy +7 more
TL;DR: A novel cellular function for retinoid receptor pathways is identified and it is suggested that selective retinoids might be of interest for controlling antigen presentation.
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Dendritic cells are early cellular targets of Listeria monocytogenes after intestinal delivery and are involved in bacterial spread in the host.
Bénédicte Pron,Claire Boumaila,Francis Jaubert,Patrick Berche,Geneviève Milon,Frederic Geissmann,Jean-Louis Gaillard +6 more
TL;DR: Evidence is provided that dendritic cells are major cellular targets of L. monocytogenes in PPs and that DCs may be involved in the early dissemination of this pathogen.
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A Subset of Human Dendritic Cells Expresses IgA Fc Receptor (CD89), Which Mediates Internalization and Activation Upon Cross-Linking by IgA Complexes
Frederic Geissmann,Pierre Launay,Benoit Pasquier,Yves Lepelletier,Michelle Leborgne,Agnès Lehuen,Nicole Brousse,Renato C. Monteiro +7 more
TL;DR: It is found that interstitial-type DC may use FcαR-mediated Ag sampling in the subepithelium to check tissue integrity while Langerhans cells inside epithelial layers may neglect IgA immune complexes.
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MEF2 Is an In Vivo Immune-Metabolic Switch
Rebecca I. Clark,Rebecca I. Clark,Sharon W. S. Tan,Claire B. Péan,Urmas Roostalu,Valérie Vivancos,Kévin Bronda,Martina Pilátová,Jingqi Fu,David W. Walker,Rebecca Berdeaux,Frederic Geissmann,Marc Dionne +12 more
TL;DR: It is found that MEF2 is phosphorylated at a conserved site in healthy flies and promotes expression of lipogenic and glycogenic enzymes and is thus a critical transcriptional switch in the adult fat body between metabolism and immunity.
Journal ArticleDOI
Immune Monitoring of Trans-endothelial Transport by Kidney-Resident Macrophages
Efstathios G. Stamatiades,Marie-Ève Tremblay,Mathieu Bohm,Lucile Crozet,Kanchan Bisht,Daniela Kao,Carolina Coelho,Xiying Fan,William T. Yewdell,Anne Davidson,Peter S. Heeger,Sandra S. Diebold,Falk Nimmerjahn,Frederic Geissmann,Frederic Geissmann,Frederic Geissmann +15 more
TL;DR: A kidney-specific anatomical and functional unit, formed by resident macrophages and peritubular capillary endothelial cells, which monitors the transport of proteins and particles into the kidney interstitium is identified.