F
Frederic Geissmann
Researcher at Memorial Sloan Kettering Cancer Center
Publications - 153
Citations - 43031
Frederic Geissmann is an academic researcher from Memorial Sloan Kettering Cancer Center. The author has contributed to research in topics: Monocyte & Macrophage. The author has an hindex of 73, co-authored 147 publications receiving 37781 citations. Previous affiliations of Frederic Geissmann include New York University & University of Paris.
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IRF4 haploinsufficiency in a family with Whipple’s disease
Antoine Guérin,Antoine Guérin,Gaspard Kerner,Gaspard Kerner,Nico Marr,Janet Markle,Florence Fenollar,Natalie Wong,Sabri Boughorbel,Danielle T. Avery,Cindy S. Ma,Salim Bougarn,Matthieu Bouaziz,Matthieu Bouaziz,Vivien Béziat,Vivien Béziat,Erika Della Mina,Erika Della Mina,Tomi Lazarov,Lisa Worley,Tina Nguyen,Etienne Patin,Caroline Deswarte,Caroline Deswarte,Rubén Martínez-Barricarte,Soraya Boucherit,Soraya Boucherit,Xavier Ayral,Sophie Edouard,Stéphanie Boisson-Dupuis,Vimel Rattina,Vimel Rattina,Benedetta Bigio,Guillaume Vogt,Frederic Geissmann,Lluis Quintana-Murci,Damien Chaussabel,Stuart G. Tangye,Didier Raoult,Laurent Abel,Laurent Abel,Laurent Abel,Jacinta Bustamante,Jean-Laurent Casanova +43 more
TL;DR: It is found that IRF4 had evolved under purifying selection and that R98W was not dominant-negative, suggesting that the IRF3 deficiency in this kindred was due to haploinsufficiency, and haplo insufficiency at theIRF4 locus selectively underlies WD in this multiplex French kindred.
Journal ArticleDOI
RA-MAP, molecular immunological landscapes in early rheumatoid arthritis and healthy vaccine recipients
John T. Isaacs,S.M. Brockbank,Ayako Wakatsuki Pedersen,Catharien M. U. Hilkens,Amy E. Anderson,Philip Stocks,Dennis Lendrem,Jessica Tarn,Graham R. Smith,Brandon Allen,John Casement,Julie Diboll,Rachel A. Harry,Faye A. H. Cooles,Andrew P. Cope,Gemma Simpson,Ruth E. Toward,Hayley Noble,Angela Parke,Wing Kei Wu,Fiona Clarke,David Scott,Ian M. Scott,James N. Galloway,Heidi Lempp,Fowzia Ibrahim,Samana Schwank,Gemma Molyneux,Tomi Lazarov,Frederic Geissmann,Carl S. Goodyear,Iain B. McInnes,Iona Donnelly,A. Gilmour,Aysin Tulunay Virlan,Duncan Porter,Frederique Ponchel,Paul Emery,Jehan J. El-Jawhari,Rekha Parmar,Michael P. McDermott,Benjamin A Fisher,Stephen P. Young,P. Jones,Karim Raza,Andrew Filer,Costantino Pitzalis,Michael R. Barnes,David Robin Watson,Rafael Henkin,Georgina Thorborn,Liliane Fossati-Jimack,Stephen Kelly,Frances Humby,Michele Bombardieri,Sharmila Rana,Zhilong Jia,Katriona Goldmann,Myles Lewis,Sandra Mei Wen Ng,Adriano Barbosa-Silva,Evan Tzanis,Amaya Gallagher-Syed,Christopher Jones,Michael R. Ehrenstein,Gioia Altobelli,Sandra Martins,D. X. Nguyen,Humayara Ali,Coziana Ciurtin,Maya H Buch,Deborah P M Symmons,Jane Worthington,Ian N. Bruce,Jamie C. Sergeant,Suzanne M M Verstappen,F. Stirling,Adwoa Hughes-Morley,Brian D. M. Tom,Vernon T. Farewell,Yujie Zhong,Peter C. Taylor,Christopher D. Buckley,Sarah Keidel,Carolyn A. Cuff,Marc Antoine Levesque,Andrew Truman Long,Zheng Liu,Samantha Lipsky,Bohdan P. Harvey,Michael Macoritto,F. Hong,S. Kaymakçalan,Wayne Tsuji,Tony Sabin,Neil I. Ward,Susan Talbot,D Padhji,Matthew A. Sleeman,Donna K. Finch,Athula Herath,Catharina Lindholm,Martin Jenkins,Meilien Ho,Sally Hollis,Chris Le Marshall,Gerry Parker,Matt Page,H Edwards,A. I. Cuza,Neil Gozzard,Ioannis Pandis,Anthony Rowe,Francisco Bonachela Capdevila,Matthew J. Loza,Mark E. Curran,Denny Verbeeck,Dan Baker,Christopher M Mela,Ivana Vranic,Catherine T. Mela,Stephen Wright,Lucy Rowell,E. Vernon,N Joseph,Neil Payne,Ravi Rao,Michael Binks,Alexandra Belson,Valerie J. Ludbrook,Kirsty Hicks,Hannah Tipney,Joanne Ellis,Samiul Hasan,Arnaud Didierlaurent,Wivine Burny,Andrea C. Haynes,Christopher Larminie,Ray Harris,Daniela Dastros-Pitei,Claudio Carini,Blerina Kola,Scott A. Jelinsky,Martin R. Hodge,Mateusz Maciejewski,Daniel Ziemek,Peter Schulz-Knappe,Hans-Dieter Zucht,Petra Budde,Mark Coles,James Butler,Simon Read +151 more
TL;DR: In this article , the authors performed comprehensive clinical and molecular profiling of 267 RA patients and 52 healthy vaccine recipients for up to 18 months to establish a high quality sample biobank including plasma, serum, peripheral blood cells, urine, genomic DNA, RNA from whole blood, lymphocyte and monocyte subsets.
Journal ArticleDOI
IL-13 Is More Efficient than IL-4 for Recruiting Langerhans Cell Precursors from Peripheral CD14+ Monocytes
Nicolas Bechetoille,Jenny Valladeau,Frederic Geissmann,Sandy Dumont,Sylvie Maréchal,Sandrine Gofflo,Valerie Andre,Daniel Schmitt,Eric Perrier,Colette Dezutter-Dambuyant +9 more
TL;DR: IL-13 in combination with GM-CSF/TGF-β1/TNF-α favors CD14+ monocyte differentiation into LC which display numerous BG.
Peer ReviewDOI
Author response: IRF4 haploinsufficiency in a family with Whipple’s disease
Antoine Guérin,Antoine Guérin,Gaspard Kerner,Gaspard Kerner,Nico Marr,Janet Markle,Florence Fenollar,Natalie Wong,Natalie Wong,Sabri Boughorbel,Danielle T. Avery,Danielle T. Avery,Cindy S. Ma,Cindy S. Ma,Salim Bougarn,Matthieu Bouaziz,Matthieu Bouaziz,Vivien Béziat,Vivien Béziat,Erika Della Mina,Erika Della Mina,Carmen Oleaga-Quintas,Carmen Oleaga-Quintas,Tomi Lazarov,Lisa Worley,Lisa Worley,Tina Nguyen,Tina Nguyen,Etienne Patin,Etienne Patin,Caroline Deswarte,Caroline Deswarte,Rubén Martínez-Barricarte,Soraya Boucherit,Soraya Boucherit,Xavier Ayral,Sophie Edouard,Stéphanie Boisson-Dupuis,Stéphanie Boisson-Dupuis,Stéphanie Boisson-Dupuis,Vimel Rattina,Vimel Rattina,Benedetta Bigio,Guillaume Vogt,Frederic Geissmann,Frederic Geissmann,Lluis Quintana-Murci,Lluis Quintana-Murci,Damien Chaussabel,Stuart G. Tangye,Stuart G. Tangye,Didier Raoult,Laurent Abel,Laurent Abel,Laurent Abel,Jacinta Bustamante,Jean-Laurent Casanova +56 more