F
Frederic Geissmann
Researcher at Memorial Sloan Kettering Cancer Center
Publications - 153
Citations - 43031
Frederic Geissmann is an academic researcher from Memorial Sloan Kettering Cancer Center. The author has contributed to research in topics: Monocyte & Macrophage. The author has an hindex of 73, co-authored 147 publications receiving 37781 citations. Previous affiliations of Frederic Geissmann include New York University & University of Paris.
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Journal ArticleDOI
Macrophage ontogeny in the control of adipose tissue biology.
Nehemiah Cox,Frederic Geissmann +1 more
TL;DR: The purpose of this review is to provide a brief history of macrophages in control of adipose tissue metabolism with the emphasis on the importance of Macrophage ontogeny.
Journal ArticleDOI
Histone deacetylase 3 controls lung alveolar macrophage development and homeostasis
Yi Yao,Queping Liu,Queping Liu,Indra Adrianto,Xiaojun Wu,James E. Glassbrook,James E. Glassbrook,Namir Khalasawi,Congcong Yin,Qijun Yi,Zheng Dong,Frederic Geissmann,Li Zhou,Qing-Sheng Mi +13 more
TL;DR: It is shown that histone deacetylase 3 (HDAC3) is a key epigenetic factor required for AM embryonic development, postnatal homeostasis, maturation, and regeneration from BM.
Journal ArticleDOI
Inherited human c-Rel deficiency disrupts myeloid and lymphoid immunity to multiple infectious agents
Romain Lévy,David Langlais,Vivien Béziat,Vivien Béziat,Franck Rapaport,Geetha Rao,Tomi Lazarov,Mathieu Bourgey,Yu Jerry Zhou,Coralie Briand,Kunihiko Moriya,Fatima Ailal,Danielle T. Avery,Janet Markle,Ai Ing Lim,Masato Ogishi,Rui Yang,Simon J. Pelham,Mehdi Emam,Mélanie Migaud,Caroline Deswarte,Tanwir Habib,Luis R. Saraiva,Eman Abou Moussa,Andrea Guennoun,Bertrand Boisson,Bertrand Boisson,Serkan Belkaya,Rubén Martínez-Barricarte,Jérémie Rosain,Aziz Belkadi,Sylvain Breton,Kathryn Payne,Ibtihal Benhsaien,Alessandro Plebani,Vassilios Lougaris,James P. Di Santo,Bénédicte Neven,Laurent Abel,Laurent Abel,Cindy S. Ma,Ahmed Aziz Bousfiha,Nico Marr,Jacinta Bustamante,Jacinta Bustamante,Kang Liu,Philippe Gros,Frederic Geissmann,Stuart G. Tangye,Jean-Laurent Casanova,Anne Puel,Anne Puel +51 more
TL;DR: In this paper, a child with severe viral, bacterial, fungal, and parasitic diseases was homozygous for a loss-of-function mutation of REL, encoding c-Rel, which is selectively expressed in lymphoid and myeloid cells.
Journal ArticleDOI
Roles of lymphoid cells in the differentiation of Langerhans dendritic cells in mice.
TL;DR: It is concluded that the presence of T cells is not required for the differentiation and migration of resident skin DC but is critical for the maintenance of DC and LC migrating into the LNs.
Aspects cliniques et physiopathologiques de l'histiocytose langerhansienne. Une prolifération clonale de cellules dendritiques de Langerhans
Frederic Geissmann,Jean-François Emile,Jean Donadieu,Pascal Andry,Caroline Thomas,Nicole Brousse +5 more
TL;DR: L'histiocytose langerhansienne (HL) est une proliferation clonale de cellules de LangerHans atteignant l'enfant and l'adulte jeune dont l'incidence est de 1,08 pour 200 000 enfants par an.