G
Gail L. Rosen
Researcher at Drexel University
Publications - 125
Citations - 4493
Gail L. Rosen is an academic researcher from Drexel University. The author has contributed to research in topics: Metagenomics & Feature selection. The author has an hindex of 23, co-authored 114 publications receiving 3461 citations. Previous affiliations of Gail L. Rosen include Georgia Institute of Technology & Rappaport Faculty of Medicine.
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Journal ArticleDOI
Opportunities and obstacles for deep learning in biology and medicine.
Travers Ching,Daniel Himmelstein,Brett K. Beaulieu-Jones,Alexandr A. Kalinin,Brian T. Do,Gregory P. Way,Enrico Ferrero,Paul-Michael Agapow,Michael Zietz,Michael M. Hoffman,Michael M. Hoffman,Wei Xie,Gail L. Rosen,Benjamin J. Lengerich,Johnny Israeli,Jack Lanchantin,Stephen Woloszynek,Anne E. Carpenter,Avanti Shrikumar,Jinbo Xu,Evan M. Cofer,Evan M. Cofer,Christopher A. Lavender,Srinivas C. Turaga,Amr Alexandari,Zhiyong Lu,David J. Harris,Dave DeCaprio,Yanjun Qi,Anshul Kundaje,Yifan Peng,Laura K. Wiley,Marwin H. S. Segler,Simina M. Boca,S. Joshua Swamidass,Austin Huang,Anthony Gitter,Anthony Gitter,Casey S. Greene +38 more
TL;DR: It is found that deep learning has yet to revolutionize biomedicine or definitively resolve any of the most pressing challenges in the field, but promising advances have been made on the prior state of the art.
Journal ArticleDOI
Environmental and ecological factors that shape the gut bacterial communities of fish: a meta‐analysis
Karen E. Sullam,Steven Essinger,Catherine A. Lozupone,Michael P. O'Connor,Gail L. Rosen,Rob Knight,Rob Knight,Susan S. Kilham,Jacob A. Russell +8 more
TL;DR: In this paper, the authors examined the influence of abiotic and biotic factors on the gut bacterial communities of fish from different taxa, trophic levels and habitats, and found that fish harbor more specialized gut communities than previously recognized.
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Comprehensive benchmarking and ensemble approaches for metagenomic classifiers.
Alexa B. R. McIntyre,Rachid Ounit,Ebrahim Afshinnekoo,Ebrahim Afshinnekoo,Robert J. Prill,Elizabeth Henaff,Noah Alexander,Samuel S. Minot,David Danko,Jonathan Foox,Sofia Ahsanuddin,Scott Tighe,Nur A. Hasan,Poorani Subramanian,Kelly Moffat,Shawn Levy,Stefano Lonardi,Nick Greenfield,Rita R. Colwell,Gail L. Rosen,Christopher E. Mason +20 more
TL;DR: It is shown that proper experimental design and analysis parameters can reduce false positives, provide greater resolution of species in complex metagenomic samples, and improve the interpretation of results.
Journal ArticleDOI
NBC: the Naïve Bayes Classification tool webserver for taxonomic classification of metagenomic reads
TL;DR: A webserver that implements the naïve Bayes classifier (NBC) to classify all metagenomic reads to their best taxonomic match is introduced and results indicate that NBC can assign next-generation sequencing reading to their taxonomic classification and can find significant populations of genera that other classifiers may miss.
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Using the RDP classifier to predict taxonomic novelty and reduce the search space for finding novel organisms.
TL;DR: It is concluded that selecting a read-length appropriate RDP bootstrap score can significantly reduce the search space for identifying novel genera and higher levels in taxonomy and the detector is a good predictor to determine novel abundant taxa.